Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA6 | P23280 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2649379 | 0.79 | KMT2A (0.36) | IMPDH2CYP2A6KMT2AMEN1KDM4E | |
| SCHEMBL28682429 | 0.78 | MEN1 (0.41) | IMPDH2CYP2A6KMT2AMEN1KDM4E | |
| SCHEMBL9028765 | 0.76 | TSHR (0.43) | IMPDH2CYP2A6KMT2AMEN1KDM4E | |
| SCHEMBL27958818 | 0.75 | MEN1 (0.38) | IMPDH2CYP2A6KMT2AMEN1KDM4E | |
| SCHEMBL2654930 | 0.73 | MEN1 (0.37) | IMPDH2CYP2A6KMT2AMEN1KDM4E | |
| SCHEMBL2650310 | 0.72 | TSHR (0.45) | KMT2AMEN1KDM4ENPC1L3MBTL1 | |
| SCHEMBL982388 | 0.71 | KMT2A (0.61) | IMPDH2CYP2A6KMT2AMEN1KDM4E | |
| SCHEMBL29786760 | 0.71 | KMT2A (0.61) | IMPDH2CYP2A6KMT2AMEN1KDM4E | |
| SCHEMBL23522302 | 0.70 | ELANE (0.37) | IMPDH2CYP2A6KMT2AMEN1KDM4E | |
| SCHEMBL23119534 | 0.66 | CA1 (0.39) | CA1CA2CA9KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-1140823-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039088-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-07-06 | — | — | WO | disclosed |