Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11054382 | 0.83 | TSHR (0.50) | TSHRALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL3174498 | 0.82 | ALDH1A1 (0.44) | TSHRALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL27692154 | 0.77 | TSHR (0.45) | TSHRALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL25156303 | 0.76 | KMT2A (0.52) | TSHRALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL31360448 | 0.76 | KMT2A (0.52) | TSHRALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL15203285 | 0.76 | KMT2A (0.52) | TSHRALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL9028765 | 0.75 | TSHR (0.43) | TSHRALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL28682429 | 0.74 | MEN1 (0.41) | TSHRALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL12930787 | 0.74 | TSHR (0.44) | TSHRALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL363983 | 0.73 | TSHR (0.48) | TSHRALDH1A1LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |