Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CCKBR | P32239 | 14/20 | 0.49 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26466613 | 0.89 | CACNA1H (0.52) | CACNA1HKMT2A | |
| SCHEMBL26464500 | 0.86 | CACNA1H (0.70) | CACNA1HKMT2ACCKBRKCNT1 | |
| SCHEMBL26466245 | 0.85 | HTT (0.55) | CACNA1HKMT2A | |
| SCHEMBL26466230 | 0.85 | HTT (0.55) | CACNA1HKMT2A | |
| SCHEMBL26466418 | 0.85 | HTT (0.55) | CACNA1HKMT2A | |
| SCHEMBL26466621 | 0.84 | CACNA1H (0.47) | CACNA1HCCKBR | |
| SCHEMBL26466216 | 0.84 | CACNA1H (0.47) | CACNA1HCCKBR | |
| SCHEMBL26466398 | 0.83 | CACNA1H (0.49) | CACNA1H | |
| SCHEMBL26467008 | 0.83 | ALDH1A1 (0.53) | CACNA1HKMT2A | |
| SCHEMBL26498839 | 0.82 | CACNA1H (0.62) | CACNA1HKMT2AKCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |