Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26466230 | 0.88 | HTT (0.55) | ALDH1A1HPGDTSHRSMN1; SMN2MAPT | |
| SCHEMBL26466245 | 0.88 | HTT (0.55) | ALDH1A1HPGDTSHRSMN1; SMN2MAPT | |
| SCHEMBL26466418 | 0.88 | HTT (0.55) | ALDH1A1HPGDTSHRSMN1; SMN2MAPT | |
| SCHEMBL26466917 | 0.85 | SIGMAR1 (0.46) | HPGDTSHRMAPTCACNA1HL3MBTL1 | |
| SCHEMBL26466913 | 0.84 | L3MBTL1 (0.48) | ALDH1A1LMNAMAPK1SMN1; SMN2MAPT | |
| SCHEMBL26466402 | 0.83 | CACNA1H (0.65) | CACNA1HKMT2A | |
| SCHEMBL26466613 | 0.83 | CACNA1H (0.52) | ALDH1A1MAPTCACNA1HKMT2AMEN1 | |
| SCHEMBL26466921 | 0.82 | CACNA1H (0.41) | HPGDTSHRCACNA1HKMT2AL3MBTL1 | |
| SCHEMBL26466611 | 0.82 | HTT (0.55) | ALDH1A1HPGDTSHRSMN1; SMN2MAPT | |
| SCHEMBL26466621 | 0.81 | CACNA1H (0.47) | ALDH1A1LMNAMAPTCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |