Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 8/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.35 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26466222 | 0.89 | CACNA1H (0.54) | CACNA1HLTA4HMEN1KMT2ALMNA | |
| SCHEMBL26466406 | 0.89 | CACNA1H (0.54) | CACNA1HLTA4HMEN1KMT2ALMNA | |
| SCHEMBL26466237 | 0.89 | CACNA1H (0.54) | CACNA1HLTA4HMEN1KMT2ALMNA | |
| SCHEMBL26466613 | 0.87 | CACNA1H (0.52) | CACNA1HCYP2D6KCNH2LTA4HMEN1 | |
| SCHEMBL26466598 | 0.86 | CACNA1H (0.46) | CACNA1HLTA4HMEN1KMT2AKCNJ5 | |
| SCHEMBL26466207 | 0.86 | CACNA1H (0.46) | CACNA1HLTA4HMEN1KMT2AKCNJ5 | |
| SCHEMBL26466390 | 0.84 | CACNA1H (0.49) | CACNA1HCYP2D6KCNH2LTA4HCACNA1I | |
| SCHEMBL26466398 | 0.84 | CACNA1H (0.49) | CACNA1HCYP2D6KCNH2LTA4HCACNA1I | |
| SCHEMBL26466387 | 0.84 | CACNA1H (0.49) | CACNA1HCYP2D6KCNH2LTA4HCACNA1I | |
| SCHEMBL26466621 | 0.83 | CACNA1H (0.47) | CACNA1HCYP2D6KCNH2LTA4HLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |