Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MB | P02144 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3115237 | 0.87 | LMNA (0.59) | LMNAALDH1A1GAATDP1MEN1 | |
| SCHEMBL7751129 | 0.87 | LMNA (0.59) | LMNAALDH1A1GAATDP1MEN1 | |
| SCHEMBL22187596 | 0.82 | ACP1 (0.46) | LMNAALDH1A1GAATDP1IDO1 | |
| SCHEMBL319174 | 0.81 | LMNA (0.52) | LMNAALDH1A1GAATDP1IDO1 | |
| SCHEMBL26467186 | 0.81 | IDO1 (0.45) | LMNAALDH1A1GAATDP1IDO1 | |
| SCHEMBL26467249 | 0.81 | IDO1 (0.45) | LMNAALDH1A1GAATDP1IDO1 | |
| SCHEMBL18751502 | 0.80 | LMNA (0.52) | LMNAALDH1A1GAATDP1IDO1 | |
| SCHEMBL13061725 | 0.80 | LMNA (0.52) | LMNAALDH1A1GAATDP1IDO1 | |
| SCHEMBL21487494 | 0.79 | LMNA (0.50) | LMNAALDH1A1GAATDP1IDO1 | |
| SCHEMBL26467006 | 0.78 | IDO1 (0.43) | LMNAALDH1A1IDO1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072143-A1 | CAMPTOTHECIN DERIVATIVE INTERMEDIATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海弼领生物技术有限公司 | 2023-05-04 | — | — | WO | disclosed |