Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11136694 | 0.87 | LMNA (0.52) | LMNAHDAC1CA1CA2CA9 | |
| SCHEMBL11564168 | 0.81 | LMNA (0.46) | IDO1LMNAHDAC1CA1CA2 | |
| SCHEMBL22187596 | 0.81 | ACP1 (0.46) | IDO1LMNAHDAC1ALDH1A1HDAC6 | |
| SCHEMBL11561253 | 0.81 | LMNA (0.46) | IDO1LMNAHDAC1ALDH1A1HDAC3 | |
| SCHEMBL26467103 | 0.81 | LMNA (0.50) | IDO1LMNAHDAC1CA1CA2 | |
| SCHEMBL319174 | 0.80 | LMNA (0.52) | IDO1LMNAHDAC1CA1CA2 | |
| SCHEMBL26467186 | 0.79 | IDO1 (0.45) | IDO1LMNAHDAC1ALDH1A1HDAC6 | |
| SCHEMBL11564984 | 0.78 | LMNA (0.43) | LMNAHDAC1CA1CA2CA9 | |
| SCHEMBL11561398 | 0.78 | LMNA (0.43) | LMNAHDAC1ALDH1A1HDAC3HDAC2 | |
| SCHEMBL26467006 | 0.77 | IDO1 (0.43) | IDO1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072143-A1 | CAMPTOTHECIN DERIVATIVE INTERMEDIATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海弼领生物技术有限公司 | 2023-05-04 | — | — | WO | disclosed |