Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2648694 | 0.85 | GCGR (0.38) | ALDH1A1LMNASMN1; SMN2POLBHTR6 | |
| SCHEMBL8685682 | 0.82 | SLC2A1 (0.52) | ALDH1A1LMNASMN1; SMN2TDP1SLC2A1 | |
| SCHEMBL8687683 | 0.80 | ALDH1A1 (0.56) | ALDH1A1LMNASMN1; SMN2TDP1POLB | |
| SCHEMBL2648704 | 0.77 | NPC1 (0.41) | POLBKMT2A | |
| SCHEMBL8685545 | 0.76 | FABP6 (0.41) | ALDH1A1LMNASMN1; SMN2TDP1SCN5A | |
| SCHEMBL8685406 | 0.74 | APP (0.49) | ALDH1A1LMNASMN1; SMN2TDP1POLB | |
| SCHEMBL29955958 | 0.72 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2TDP1POLB | |
| SCHEMBL1253456 | 0.72 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2TDP1POLB | |
| SCHEMBL8394619 | 0.72 | APP (0.63) | ALDH1A1LMNASMN1; SMN2TDP1HTR6 | |
| SCHEMBL8690879 | 0.72 | HDAC3 (0.46) | ALDH1A1LMNASMN1; SMN2TDP1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-1140823-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039088-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-07-06 | — | — | WO | disclosed |