Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 3/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6800946 | 0.83 | ALDH1A1 (0.57) | SLC22A12ALDH1A1SMN1; SMN2LMNATDP1 | |
| SCHEMBL2646725 | 0.82 | ALDH1A1 (0.39) | SLC2A1APPALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8394619 | 0.79 | APP (0.63) | SLC2A1APPALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8690879 | 0.78 | HDAC3 (0.46) | SLC2A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8685406 | 0.78 | APP (0.49) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8809703 | 0.78 | HPGD (0.53) | MEN1KMT2AHPGD | |
| SCHEMBL8809700 | 0.78 | HPGD (0.53) | MEN1KMT2AHPGD | |
| SCHEMBL31668270 | 0.75 | SIRT2 (0.38) | APPALDH1A1SMN1; SMN2LMNATDP1 | |
| SCHEMBL8685545 | 0.74 | FABP6 (0.41) | APPALDH1A1SMN1; SMN2LMNATDP1 | |
| SCHEMBL2646681 | 0.74 | ALDH1A1 (0.52) | APPALDH1A1SMN1; SMN2LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |