SCHEMBL26467384

SCHEMBL26467384

Nc1cc(F)c(Br)c(I)c1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
KDM1A O60341 2/20 0.33
KDM1B Q8NB78 1/20 0.33
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA3 P07451 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL238421 0.82 KDM1A (0.44) GAAMAPTKDM1AKDM1BCA1
SCHEMBL24491001 0.82 GAA (0.43) GAAMAPTCA1CA2CA9
SCHEMBL18373638 0.75 CA1 (0.33) CA1CA2CA3CA9
SCHEMBL1042776 0.75 ALDH1A1 (0.39) GAAMAPTKDM1AKDM1BCA1
SCHEMBL14744248 0.71 ALDH1A1 (0.38) GAAMAPTKDM1AKDM1B
SCHEMBL20783224 0.71 ALDH1A1 (0.38) CA1CA2CA3CA9
SCHEMBL1806961 0.71 CYP3A4 (0.46) GAAMAPTKDM1AKDM1BCA1
SCHEMBL23174468 0.71 GAA (0.46) GAAMAPTCA1CA2CA3
SCHEMBL11111790 0.71 CYP3A4 (0.46) GAAMAPTCA1CA2CA9
SCHEMBL2360976 0.71 ALDH1A1 (0.33) GAAMAPTCA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023072143-A1 CAMPTOTHECIN DERIVATIVE INTERMEDIATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海弼领生物技术有限公司 2023-05-04 WO disclosed