Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 3/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.48 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19448892 | 0.86 | CETP (0.49) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL31606389 | 0.81 | HPGD (0.41) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL6029980 | 0.80 | PDK1 (0.53) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL914296 | 0.80 | PDK1 (0.70) | PDK1PDK2PDK3PDK4MAPT | |
| Hydrochloric Acid SCHEMBL28203570 | 0.78 | PDK1 (0.68) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL23885453 | 0.78 | PDK1 (0.50) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL30254224 | 0.78 | PDK1 (0.50) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL10397824 | 0.78 | HPGD (0.46) | MAPTHTTRAB9ANPC1ALDH1A1 | |
| SCHEMBL23634089 | 0.76 | HPGD (0.45) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27385960 | 0.76 | LCK (0.43) | RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023070114-A2 | REVERSIBLE LYSINE COVALENT MODIFIERS OF EGFR AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2023-04-27 | — | — | WO | disclosed |