Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.70 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.70 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.70 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28203570 | 0.98 | PDK1 (0.68) | PDK1PDK2PDK3PDK4RAB9A | |
| SCHEMBL26623837 | 0.87 | PDK1 (0.73) | PDK1PDK2PDK3PDK4RAB9A | |
| SCHEMBL6029980 | 0.85 | PDK1 (0.53) | PDK1PDK2PDK3PDK4RAB9A | |
| SCHEMBL397003 | 0.82 | PDK1 (0.67) | PDK1PDK2PDK3PDK4RAB9A | |
| SCHEMBL23885453 | 0.82 | PDK1 (0.50) | PDK1PDK2PDK3PDK4RAB9A | |
| SCHEMBL30254224 | 0.82 | PDK1 (0.50) | PDK1PDK2PDK3PDK4RAB9A | |
| SCHEMBL28846032 | 0.82 | PDK1 (0.67) | PDK1PDK2PDK3PDK4RAB9A | |
| SCHEMBL29980058 | 0.82 | HPGD (0.54) | PDK1PDK2PDK3PDK4RAB9A | |
| SCHEMBL3600530 | 0.81 | L3MBTL1 (0.59) | PDK1PDK2PDK3PDK4HPGD | |
| SCHEMBL6349201 | 0.81 | PDK1 (0.70) | PDK1PDK2PDK3PDK4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230337677-A1 | ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2023-10-26 | — | — | US | disclosed |
| EP-3169662-B1 | SUBSTITUTED VINYL- AND ALKINYL-CYANOCYCLOALKANOLS AND VINYL- AND ALKINYL-CYANOHETEROCYCLOALKANOLS AS AGENTS TO COMBAT ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2018-07-11 | — | — | EP | disclosed |
| EP-2610247-B1 | Arylsulfonyl pyrazoline carboxamidine derivatives as 5-HT6 antagonists | ABBVIE BAHAMAS LTD (BS) | 2016-05-25 | — | — | EP | disclosed |
| EP-2610247-B1 | Arylsulfonyl pyrazoline carboxamidine derivatives as 5-HT6 antagonists | ABBVIE BAHAMAS LTD (BS) | 2016-05-25 | — | — | EP | disclosed |
| EP-2265589-B1 | ARYLSULFONYL PYRAZOLINE CARBOXAMIDINE DERIVATIVES AS 5-HT6 ANTAGONISTS | ABBVIE BAHAMAS LTD (BS) | 2016-01-27 | — | — | EP | disclosed |
| EP-2265589-B1 | ARYLSULFONYL PYRAZOLINE CARBOXAMIDINE DERIVATIVES AS 5-HT6 ANTAGONISTS | ABBVIE BAHAMAS LTD (BS) | 2016-01-27 | — | — | EP | disclosed |
| US-9126942-B2 | Arylsulfonyl pyrazoline carboxamidine derivatives as 5-HT6 antagonists | ABBVIE BAHAMAS LIMITED (BS) | 2015-09-08 | — | — | US | disclosed |
| US-9126942-B2 | Arylsulfonyl pyrazoline carboxamidine derivatives as 5-HT6 antagonists | ABBVIE BAHAMAS LIMITED (BS) | 2015-09-08 | — | — | US | disclosed |
| US-20150051239-A1 | ARYLSULFONYL PYRAZOLINE CARBOXAMIDINE DERIVATIVES AS 5-HT6 ANTAGONISTS | ABBVIE BAHAMAS LIMITED (BS) | 2015-02-19 | — | — | US | disclosed |
| US-20150051239-A1 | ARYLSULFONYL PYRAZOLINE CARBOXAMIDINE DERIVATIVES AS 5-HT6 ANTAGONISTS | ABBVIE BAHAMAS LIMITED (BS) | 2015-02-19 | — | — | US | disclosed |
| US-20080027067-A1 | Heterocyclic derivatives as modulators of ion channels | VERTEX PHARMACEUTICALS INCORPORATED | 2008-01-31 | — | — | US | disclosed |
| US-20080027067-A1 | Heterocyclic derivatives as modulators of ion channels | VERTEX PHARMACEUTICALS INCORPORATED | 2008-01-31 | — | — | US | disclosed |
| WO-2007124345-A2 | BETA-AMYLOID PET IMAGING AGENTS | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF HEALTH AND HUMAN SERVICES (US) | 2007-11-01 | — | — | WO | disclosed |
| US-7282609-B2 | Process for production of 1-aryl-5-(trifluoromethyl)-1H-tetrazoles | TOYO KASEI KOGYO COMPANY LIMITED (JP) | 2007-10-16 | — | — | US | disclosed |
| US-20070106080-A1 | Process for production of 1-aryl-5-(trifluoromethyl)-1h-tetrazoles | TOYO KASEI KOGYO COMPANY LIMITED (JP) | 2007-05-10 | — | — | US | disclosed |
| US-20070072911-A1 | Indoles and azaindoles as antiviral agents | AVOLIO SALVATORE | 2007-03-29 | — | — | US | disclosed |
| EP-1671945-A1 | PROCESS FOR PRODUCTION OF 1-ARYL-5-(TRIFLUOROMETHYL)-1H- TETRAZOLES | Toyo Kasei Kogyo Company Limited (JP) | 2006-06-21 | — | — | EP | disclosed |
| EP-0213474-A2 | Substituted toluidines, process for their preparation, pharmaceutical compositions containing them and their use as gastric secretion inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-11 | — | — | EP | disclosed |
| US-4005199-A | Substituted benzenesulfonamides as anthelmintics | MERCK & CO., INC. (US) | 1977-01-25 | — | — | US | disclosed |
| US-3987199-A | PARASITICIDES | MERCK & CO., INC. (US) | 1976-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027067-A1 | Heterocyclic derivatives as modulators of ion channels | TRPV1, KCNJ2, KCNN3 | PDK1 938/4885PDK2 1240/4885PDK3 1283/4885 |
| US-20150051239-A1 | ARYLSULFONYL PYRAZOLINE CARBOXAMIDINE DERIVATIVES AS 5-HT6 ANTAGONISTS | HTR6, HTR2C, HTR4 | PDK1 2279/4885PDK2 784/4885PDK3 2145/4885 |
| US-20070106080-A1 | Process for production of 1-aryl-5-(trifluoromethyl)-1h-tetrazoles | TH, NAT1, PAH | PDK1 3510/4885PDK2 1327/4885PDK3 2948/4885 |
| US-20070072911-A1 | Indoles and azaindoles as antiviral agents | IDO1, IDO2, NAT1 | PDK1 4424/4885PDK2 3189/4885PDK3 2815/4885 |
| US-20230337677-A1 | ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF | DDT, ACHE, AHR | PDK1 2357/4885PDK2 1573/4885PDK3 1596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.