Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 5/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 6/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL410261 | 0.96 | JAK3 (0.48) | JAK3CDK4CDK7CDK9BTK | |
| SCHEMBL2618873 | 0.96 | JAK3 (0.48) | JAK3CDK4CDK7CDK9BTK | |
| SCHEMBL17928309 | 0.96 | JAK3 (0.48) | JAK3CDK4CDK7CDK9BTK | |
| SCHEMBL20892752 | 0.92 | JAK3 (0.41) | JAK3CDK4CDK7CDK9BTK | |
| SCHEMBL20892949 | 0.92 | JAK3 (0.41) | JAK3CDK4CDK7CDK9BTK | |
| SCHEMBL21884776 | 0.85 | JAK3 (0.46) | JAK3CDK4CDK7CDK9BTK | |
| SCHEMBL20892791 | 0.84 | JAK3 (0.36) | JAK3CDK4CDK7CDK9BTK | |
| SCHEMBL410131 | 0.83 | CCR2 (0.39) | JAK3CDK4CDK7CDK9BTK | |
| SCHEMBL409255 | 0.83 | BTK (0.41) | JAK3CDK4CDK7CDK9BTK | |
| SCHEMBL24348777 | 0.82 | ALDH1A1 (0.47) | JAK3BTKEGFRCYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023070114-A2 | REVERSIBLE LYSINE COVALENT MODIFIERS OF EGFR AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2023-04-27 | — | — | WO | disclosed |