Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211687 | 0.80 | ALDH1A1 (0.41) | SLC6A3ALDH1A1LMNACHRM2ADRA2B | |
| SCHEMBL3741295 | 0.80 | FFAR1 (0.42) | ADRB2FFAR1SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL436858 | 0.73 | ADRB2 (0.50) | ADRB2SLC6A3SLC6A4SLC6A2FFAR2 | |
| SCHEMBL96816 | 0.73 | ADRB2 (0.50) | ADRB2FFAR1SLC6A3SLC6A2POLB | |
| Hydrochloric Acid SCHEMBL4498923 | 0.71 | ADRB2 (0.48) | ADRB2SLC6A3SLC6A4SLC6A2POLB | |
| SCHEMBL9419163 | 0.69 | ADRB2 (0.46) | ADRB2SLC6A3SLC6A4SLC6A2POLB | |
| SCHEMBL22517167 | 0.69 | ADRB2 (0.46) | ADRB2SLC6A3SLC6A4SLC6A2POLB | |
| SCHEMBL12243879 | 0.69 | AOC3 (0.53) | ADRB2SLC6A3SLC6A4SLC6A2POLB | |
| SCHEMBL13995177 | 0.69 | ADRB2 (0.58) | ADRB2SLC6A3SLC6A4SLC6A2L3MBTL1 | |
| SCHEMBL11611030 | 0.68 | ADRB2 (0.45) | ADRB2SLC6A3SLC6A2POLBFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169312-A2 | GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000058293-A2 | GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2000-10-05 | — | — | WO | disclosed |