SCHEMBL26469464

SCHEMBL26469464

COC(=O)c1nc(-c2cccs2)sc1-c1cccs1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERCC1 P07992 1/20 0.51
FEN1 P39748 1/20 0.51
ERCC4 Q92889 1/20 0.51
KDM4E B2RXH2 9/20 0.50
ALDH1A1 P00352 8/20 0.50
MAPT P10636 4/20 0.50
HSD17B10 Q99714 3/20 0.50
NPC1 O15118 3/20 0.50
GAA P10253 1/20 0.48
HPGD P15428 3/20 0.46
AHR P35869 1/20 0.46
RAB9A P51151 3/20 0.46
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
TP53 P04637 1/20 0.45
ATM Q13315 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
PPARG P37231 1/20 0.43
NCOA2 Q15596 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2162886 0.74 KDM4E (0.58) KDM4EALDH1A1MAPTHSD17B10NPC1
SCHEMBL6496780 0.72 KDM4E (0.64) ERCC1FEN1ERCC4KDM4EALDH1A1
SCHEMBL11075687 0.71 ERCC1 (0.48) ERCC1FEN1ERCC4KDM4EALDH1A1
SCHEMBL30625687 0.71 KMT2A (0.50) ERCC1FEN1ERCC4KDM4EALDH1A1
SCHEMBL31055049 0.71 KDM4E (0.68) ERCC1FEN1ERCC4KDM4EALDH1A1
SCHEMBL352099 0.71 KDM4E (0.55) ERCC1FEN1ERCC4KDM4EALDH1A1
SCHEMBL3833902 0.70 ERCC1 (0.60) ERCC1FEN1ERCC4KDM4EALDH1A1
SCHEMBL13174730 0.70 ERCC1 (0.70) ERCC1FEN1ERCC4KDM4EALDH1A1
SCHEMBL25545910 0.70 KDM4E (0.52) ERCC1FEN1ERCC4KDM4EALDH1A1
SCHEMBL2162193 0.70 NPC1 (0.70) KDM4EALDH1A1MAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023070569-A1 ESTER GROUP THIAZOLE-TYPE WIDE BAND-GAP POLYMER AND USE THEREOF IN PHOTOELECTRIC DEVICE 武汉工程大学 2023-05-04 WO disclosed