Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | GLA | P06280 | 1/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | CASP7 | P55210 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1235256 | 0.86 | LMNA (0.60) | KDM4EALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL1761399 | 0.82 | ALDH1A1 (0.71) | KDM4EALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL14582053 | 0.81 | ALDH1A1 (0.60) | KDM4EALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL6978748 | 0.81 | ALDH1A1 (0.60) | KDM4EALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL4280023 | 0.81 | ALDH1A1 (0.69) | KDM4EALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL4319368 | 0.81 | ALDH1A1 (1.00) | KDM4EALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL498577 | 0.81 | ALDH1A1 (0.69) | KDM4EALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL7870469 | 0.80 | ALDH1A1 (0.89) | KDM4EALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL8572753 | 0.79 | ALDH1A1 (0.96) | KDM4EALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL5903723 | 0.79 | HDAC1 (1.00) | KDM4EALDH1A1L3MBTL1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228471-A1 | MOF, MOF LINKERS AND MANUFACTURING METHOD THEREOF | UNIVERSITEIT ANTWERPEN (BE) | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228471-A1 | MOF, MOF LINKERS AND MANUFACTURING METHOD THEREOF | ILK, MTCL3, FTO | KDM4E 146/4885ALDH1A1 979/4885L3MBTL1 999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.