Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.85 |
| ▸ | POLB | P06746 | 1/20 | 0.85 |
| ▸ | GAA | P10253 | 1/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.80 |
| ▸ | MEN1 | O00255 | 3/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.80 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 3/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10933445 | 0.95 | ALDH1A1 (0.95) | ALDH1A1KDM4EPOLBGAAKMT2A | |
| SCHEMBL10780555 | 0.95 | KMT2A (0.85) | ALDH1A1KDM4EPOLBGAAKMT2A | |
| SCHEMBL267885 | 0.92 | ALDH1A1 (1.00) | ALDH1A1KDM4EPOLBGAAKMT2A | |
| SCHEMBL3660975 | 0.91 | ALDH1A1 (0.93) | ALDH1A1KDM4EPOLBGAAKMT2A | |
| SCHEMBL264913 | 0.90 | ALDH1A1 (0.91) | ALDH1A1KDM4EPOLBGAAKMT2A | |
| SCHEMBL3656127 | 0.90 | ALDH1A1 (0.91) | ALDH1A1KDM4EPOLBGAAKMT2A | |
| SCHEMBL3659209 | 0.90 | ALDH1A1 (0.91) | ALDH1A1KDM4EPOLBGAAKMT2A | |
| SCHEMBL39206 | 0.89 | KMT2A (1.00) | ALDH1A1KDM4EPOLBGAAKMT2A | |
| SCHEMBL9629674 | 0.88 | ALDH1A1 (0.71) | ALDH1A1KDM4EPOLBGAAKMT2A | |
| SCHEMBL11080174 | 0.86 | ALDH1A1 (0.84) | ALDH1A1KDM4EPOLBGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134017-B1 | Compound and use thereof | RIKEN (JP) | 2012-03-13 | — | — | US | disclosed |
| US-4594601-A | Fluoran compounds | HODOGAYA CHEMICAL CO., LTD. (JP) | 1986-06-10 | — | — | US | disclosed |
| EP-0048026-B1 | HEAT SENSITIVE RECORD SHEET | HODOGAYA CHEMICAL CO., LTD. (JP) | 1984-12-19 | — | — | EP | disclosed |
| EP-0107780-A2 | Fluoran compounds | HODOGAYA CHEMICAL CO., LTD. (JP) | 1984-05-09 | — | — | EP | disclosed |
| US-4364999-A | 2-(2-CHLOROPHENYL)AMINO-6-DI-PROPYL-OR BUTYL-AMINOFLUORAN | HODOGAYA CHEMICAL CO., LTD. (JP) | 1982-12-21 | — | — | US | disclosed |
| EP-0048026-A1 | Heat sensitive record sheet | HODOGAYA CHEMICAL CO., LTD. (JP) | 1982-03-24 | — | — | EP | disclosed |
| US-4052398-A | DIAZARHODAMINE-LACTONES, THEIR MANUFACTURE AND THEIR USE AS DYE INTERMEDIATES FOR COPYING PROCESSES | BASF AKTIENGESELLSCHAFT (DT) | 1977-10-04 | — | — | US | disclosed |