Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.93 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.93 |
| ▸ | POLB | P06746 | 1/20 | 0.93 |
| ▸ | GAA | P10253 | 1/20 | 0.93 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264913 | 0.99 | ALDH1A1 (0.91) | ALDH1A1KDM4EPOLBGAAKMT2A | |
| SCHEMBL3656127 | 0.99 | ALDH1A1 (0.91) | ALDH1A1KDM4EPOLBGAAKMT2A | |
| SCHEMBL3659209 | 0.99 | ALDH1A1 (0.91) | ALDH1A1KDM4EPOLBGAAKMT2A | |
| SCHEMBL267885 | 0.96 | ALDH1A1 (1.00) | ALDH1A1KDM4EPOLBGAAKMT2A | |
| SCHEMBL11080174 | 0.95 | ALDH1A1 (0.84) | ALDH1A1KDM4EPOLBGAAKMT2A | |
| SCHEMBL9628808 | 0.94 | ALDH1A1 (0.82) | ALDH1A1KDM4EPOLBGAAKMT2A | |
| SCHEMBL10933445 | 0.94 | ALDH1A1 (0.95) | ALDH1A1KDM4EPOLBGAAKMT2A | |
| SCHEMBL11083623 | 0.91 | ALDH1A1 (0.78) | ALDH1A1KDM4EPOLBGAAKMT2A | |
| SCHEMBL264702 | 0.91 | ALDH1A1 (0.85) | ALDH1A1KDM4EPOLBGAAKMT2A | |
| SCHEMBL11078373 | 0.89 | ALDH1A1 (0.74) | ALDH1A1KDM4EPOLBGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101939309-A | Uva filter based on ascorbic acid derivatives | MERCK PATENT GMBH | 2011-01-05 | — | — | CN | disclosed |
| US-20100322880-A1 | UVA FILTERS BASED ON ASCORBIC ACID DERIVATIVES | MERCK PATENT GMBH | 2010-12-23 | — | — | US | disclosed |
| US-20100322880-A1 | UVA FILTERS BASED ON ASCORBIC ACID DERIVATIVES | MERCK PATENT GMBH | 2010-12-23 | — | — | US | disclosed |
| EP-2238121-A1 | UVA FILTER BASED ON ASCORBIC ACID DERIVATIVES | Merck Patent GmbH (DE) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009097951-A1 | UVA FILTER BASED ON ASCORBIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2009-08-13 | — | — | WO | disclosed |
| US-5166350-A | Process for the manufacture of fluoran compounds | CIBA-GEIGY CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100322880-A1 | UVA FILTERS BASED ON ASCORBIC ACID DERIVATIVES | C1R, VDR, C1S | ALDH1A1 80/4885KDM4E 3422/4885POLB 2018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.