SCHEMBL2647110

SCHEMBL2647110

CCCCc1ccc(N)c([N+](=O)[O-])c1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SKP2 Q13309 1/20 0.56
TSHR P16473 1/20 0.53
TDP1 Q9NUW8 3/20 0.51
ALDH1A1 P00352 3/20 0.51
MAPT P10636 3/20 0.51
MEN1 O00255 2/20 0.51
POLB P06746 2/20 0.51
KMT2A Q03164 2/20 0.51
CYP3A4 P08684 1/20 0.51
ALOX15 P16050 1/20 0.51
PKM P14618 1/20 0.45
LMNA P02545 2/20 0.45
CA2 P00918 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
KCNH2 Q12809 1/20 0.43
KAT2B Q92831 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5869144 0.95 TSHR (0.51) SKP2TSHRTDP1ALDH1A1MAPT
SCHEMBL9100894 0.94 KCNH2 (0.51) SKP2TSHRTDP1ALDH1A1MAPT
SCHEMBL6365845 0.94 KCNH2 (0.51) SKP2TSHRTDP1ALDH1A1MAPT
SCHEMBL10780618 0.94 KCNH2 (0.51) SKP2TSHRTDP1ALDH1A1MAPT
SCHEMBL5952783 0.90 TSHR (0.56) SKP2TSHRTDP1ALDH1A1MAPT
SCHEMBL3549483 0.88 TDP1 (0.63) SKP2TSHRTDP1ALDH1A1MAPT
SCHEMBL11490171 0.87 MAPT (0.54) SKP2TSHRTDP1ALDH1A1MAPT
SCHEMBL12798874 0.86 TDP1 (0.62) TSHRTDP1ALDH1A1MAPTMEN1
SCHEMBL7948996 0.84 TDP1 (0.51) TSHRTDP1ALDH1A1MAPTMEN1
SCHEMBL83731 0.83 ALDH1A1 (0.50) SKP2TDP1ALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118005982-B Preparation method of fireproof high-strength plastic pipe 任丘市华信电信器材有限公司 2024-11-22 CN claimed
CN-118005982-A Preparation method of fireproof high-strength plastic pipe 扬州鑫宸建材有限公司 2024-05-10 CN claimed
CN-116622180-B Fireproof high-strength plastic pipe and preparation method thereof 河北通涛管业集团股份有限公司 2024-01-16 CN claimed
CN-116622180-A Fireproof high-strength plastic pipe and preparation method thereof 扬州鑫宸建材有限公司 2023-08-22 CN claimed
CN-108689860-A A kind of synthetic method preparing 4- butyl benzene -1,2- diamines 荆门医药工业技术研究院 2018-10-23 CN claimed
CN-118005982-B Preparation method of fireproof high-strength plastic pipe 任丘市华信电信器材有限公司 2024-11-22 CN disclosed
CN-118005982-B Preparation method of fireproof high-strength plastic pipe 任丘市华信电信器材有限公司 2024-11-22 CN disclosed
CN-118005982-A Preparation method of fireproof high-strength plastic pipe 扬州鑫宸建材有限公司 2024-05-10 CN disclosed
CN-118005982-A Preparation method of fireproof high-strength plastic pipe 扬州鑫宸建材有限公司 2024-05-10 CN disclosed
CN-114436972-B Pabendazole derivative, and preparation method and application thereof 山东大学 2024-02-13 CN disclosed
CN-116622180-B Fireproof high-strength plastic pipe and preparation method thereof 河北通涛管业集团股份有限公司 2024-01-16 CN disclosed
CN-116622180-B Fireproof high-strength plastic pipe and preparation method thereof 河北通涛管业集团股份有限公司 2024-01-16 CN disclosed
EP-0186627-A2 Orthonitroanilines and process for their preparation CIBA-GEIGY AG (CH) 1986-07-02 EP disclosed
EP-0185620-A2 Monoazo compounds CIBA-GEIGY AG (CH) 1986-06-25 EP disclosed
EP-0039367-A4 UV-ABSORBING COMPOUNDS AND PHOTOGRAPHIC ELEMENTS CONTAINING THEM. MINNESOTA MINING & MFG (US) 1982-07-12 EP disclosed
US-4323633-A BUTYLATED 2-HYDROXYPHENYL BENZOTRIAZOLE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-04-06 US disclosed
EP-0039367-A1 UV-ABSORBING COMPOUNDS AND PHOTOGRAPHIC ELEMENTS CONTAINING THEM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-11-11 EP disclosed
WO-1981001473-A1 UV-ABSORBING COMPOUNDS AND PHOTOGRAPHIC ELEMENTS CONTAINING THEM MINNESOTA MINING & MFG (US) 1981-05-28 WO disclosed
US-4060491-A 5-ALKYL BENZOTRIAZOLE MOBIL OIL CORPORATION (US) 1977-11-29 US disclosed
US-3998804-A PROCESS FOR COUPLING OF WATER-INSOLUBLE 2,4-DISUBSTITUTED PHENOLS WITH DIAZOTIZED O-NITROANILINES CIBA-GEIGY CORPORATION (US) 1976-12-21 US disclosed