Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2647110 | 0.90 | SKP2 (0.56) | TSHRTDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL12798874 | 0.89 | TDP1 (0.62) | TSHRTDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL5869144 | 0.89 | TSHR (0.51) | TSHRTDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL9100894 | 0.87 | KCNH2 (0.51) | TSHRTDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL10780618 | 0.87 | KCNH2 (0.51) | TSHRTDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL6365845 | 0.87 | KCNH2 (0.51) | TSHRTDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL11494839 | 0.86 | MAPT (0.56) | TSHRTDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL1069671 | 0.86 | TSHR (0.59) | TSHRTDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL11295679 | 0.84 | TDP1 (0.56) | TSHRTDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL992165 | 0.84 | TDP1 (0.61) | TSHRTDP1ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994012465-A1 | POLYAMIDES AND POLYPYRROLONES FOR FLUID SEPARATION MEMBRANES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1994-06-09 | — | — | WO | claimed |
| US-20130029980-A1 | FLAVIN DERIVATIVES | COISH PHILIP D G (US) | 2013-01-31 | — | — | US | disclosed |
| US-8288425-B2 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2012-10-16 | — | — | US | disclosed |
| US-8288425-B2 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2012-10-16 | — | — | US | disclosed |
| US-8288425-B2 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2012-10-16 | — | — | US | disclosed |
| US-20060014756-A1 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2006-01-19 | — | — | US | disclosed |
| US-6897208-B2 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2005-05-24 | — | — | US | disclosed |
| EP-1441725-A1 | BENZIMIDAZOLES AND ANALOGUES AND THEIR USE AS PROTEIN KINASES INHIBITORS | Aventis Pharmaceuticals Inc. (US) | 2004-08-04 | — | — | EP | disclosed |
| US-20040048868-A1 | Benzimidazoles | AVENTISUB LLC | 2004-03-11 | — | — | US | disclosed |
| WO-2003035065-A1 | BENZIMIDAZOLES AND ANALOGUES AND THEIR USE AS PROTEIN KINASES INHIBITORS | AVENTIS PHARMACEUTICALS INC (US) | 2003-05-01 | — | — | WO | disclosed |
| WO-1994012465-A1 | POLYAMIDES AND POLYPYRROLONES FOR FLUID SEPARATION MEMBRANES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1994-06-09 | — | — | WO | disclosed |
| US-5262056-A | Polyamides and polypyrrolones for fluid separation membranes | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1993-11-16 | — | — | US | disclosed |
| EP-0362725-A1 | Process for producing water insoluble azo dyes on the fibre according to the ice-colour technique | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-11 | — | — | EP | disclosed |
| US-4704452-A | YELLOW SHADES ON POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1987-11-03 | — | — | US | disclosed |
| US-4700003-A | DISPERSION DYESTUFF INTERMEDIATES | CIBA-GEIGY CORPORATION (US) | 1987-10-13 | — | — | US | disclosed |
| EP-0186627-A2 | Orthonitroanilines and process for their preparation | CIBA-GEIGY AG (CH) | 1986-07-02 | — | — | EP | disclosed |
| EP-0185620-A2 | Monoazo compounds | CIBA-GEIGY AG (CH) | 1986-06-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014756-A1 | Benzimidazoles | CDK9, BMX, SBK3 | TSHR 3828/4885TDP1 2680/4885ALDH1A1 1389/4885 |
| US-20130029980-A1 | FLAVIN DERIVATIVES | BLVRB, FLAD1, FDPS | TSHR 3098/4885TDP1 828/4885ALDH1A1 871/4885 |
| US-20040048868-A1 | Benzimidazoles | CDK9, BMX, CDKN1A | TSHR 4027/4885TDP1 1498/4885ALDH1A1 862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.