Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.90 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.90 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.67 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5014268 | 0.95 | TSHR (1.00) | TSHRALDH1A1TAAR1AOC3HRH3 | |
| SCHEMBL24735547 | 0.95 | TSHR (1.00) | TSHRALDH1A1TAAR1AOC3HRH3 | |
| SCHEMBL15900 | 0.95 | TSHR (1.00) | TSHRALDH1A1TAAR1AOC3HRH3 | |
| SCHEMBL27766437 | 0.95 | TSHR (1.00) | TSHRALDH1A1TAAR1AOC3HRH3 | |
| Iodide SCHEMBL6672021 | 0.92 | TSHR (0.94) | TSHRALDH1A1TAAR1AOC3HRH3 | |
| Hydrochloric Acid SCHEMBL6391891 | 0.92 | TSHR (0.94) | TSHRALDH1A1TAAR1AOC3HRH3 | |
| Bromide SCHEMBL414532 | 0.92 | TSHR (0.94) | TSHRALDH1A1TAAR1AOC3HRH3 | |
| SCHEMBL7911439 | 0.92 | TSHR (0.94) | TSHRALDH1A1TAAR1AOC3HRH3 | |
| Trimethylammonium SCHEMBL8195424 | 0.92 | TSHR (0.94) | TSHRALDH1A1TAAR1AOC3HRH3 | |
| SCHEMBL1158117 | 0.92 | TSHR (0.94) | TSHRALDH1A1TAAR1AOC3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-1140823-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039088-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-07-06 | — | — | WO | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |