Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 2/20 | 0.38 |
| ▸ | HMGCR | P04035 | 2/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 3/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2647289 | 0.72 | FFAR4 (0.39) | — | |
| SCHEMBL8780169 | 0.69 | HMGCR (0.53) | GLRA1HMGCR | |
| SCHEMBL8164051 | 0.66 | GLRA1 (0.57) | GLRA1RXRARXRBRXRG | |
| SCHEMBL2648946 | 0.65 | GCGR (0.44) | HMGCR | |
| SCHEMBL8854960 | 0.64 | GLRA1 (0.44) | GLRA1 | |
| SCHEMBL8780259 | 0.64 | GLRA1 (0.53) | GLRA1 | |
| SCHEMBL16785954 | 0.63 | GLRA1 (0.63) | GLRA1 | |
| SCHEMBL8855126 | 0.63 | MGAM (0.44) | GLRA1HMGCR | |
| SCHEMBL2648392 | 0.63 | L3MBTL1 (0.40) | — | |
| SCHEMBL2648389 | 0.63 | L3MBTL1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218431-B1 | GLUCAGON RECEPTOR ANTAGONISTS FOR THERAPY OF DIABETES AND CONDITIONS ASSOCIATED WITH DIABETES | BAYER CORPORATION | 2001-04-17 | — | — | US | disclosed |