Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 2/20 | 0.64 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.59 |
| ▸ | JAK2 | O60674 | 2/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.52 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL26092586 | 0.99 | PHGDH (0.63) | PHGDHAKR1C3JAK2NR1H2NR1H3 | |
| (4-Chlorophenyl)(Morpholino)Methanone SCHEMBL6937394 | 0.80 | PHGDH (1.00) | PHGDHAKR1C3F2MAPTKMT2A | |
| SCHEMBL26475622 | 0.76 | NR1H2 (0.71) | NR1H2NR1H3KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11187134 | 0.76 | NR1H2 (0.86) | JAK2NR1H2NR1H3MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL26094773 | 0.75 | NR1H2 (0.69) | NR1H2NR1H3KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL3993564 | 0.73 | PHGDH (0.63) | PHGDHAKR1C3JAK2SMN1; SMN2HPGD | |
| SCHEMBL10720943 | 0.72 | PHGDH (0.81) | PHGDHAKR1C3MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL26467177 | 0.72 | PLK4 (0.53) | JAK2KMT2ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL28296651 | 0.71 | HPGD (0.86) | PHGDHAKR1C3MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL4908920 | 0.70 | RIPK1 (0.55) | PHGDHAKR1C3JAK2SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023073115-A1 | PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-05-04 | — | — | WO | disclosed |