⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22078620 | 0.80 | QPCT (0.41) | — | |
| SCHEMBL269487 | 0.79 | PRKD3 (0.30) | — | |
| SCHEMBL1211678 | 0.74 | ROCK2 (0.39) | — | |
| SCHEMBL22079234 | 0.74 | ROCK2 (0.39) | — | |
| SCHEMBL22079236 | 0.74 | ROCK2 (0.39) | — | |
| SCHEMBL1211675 | 0.74 | ROCK2 (0.39) | — | |
| SCHEMBL7968994 | 0.73 | SCN10A (0.43) | — | |
| SCHEMBL265062 | 0.73 | ALDH1A1 (0.41) | — | |
| SCHEMBL3929548 | 0.71 | OGA (0.39) | — | |
| SCHEMBL264864 | 0.70 | SCN10A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134004-B2 | Substituted N-bicyclicalkyl bicycliccarboxyamide compounds | PFIZER INC. (US) | 2012-03-13 | — | — | US | disclosed |
| US-20090253740-A1 | SUBSTITUTED N-BICYCLICALKYL BICYCLICCARBOXYAMIDE COMPOUNDS | PFIZER INC | 2009-10-08 | — | — | US | disclosed |
| US-7514457-B2 | Substituted aryloxymethyl bicyclicmethyl acetamide compounds | PFIZER INC. (US) | 2009-04-07 | — | — | US | disclosed |
| US-20060270682-A1 | Substituted Aryloxymethyl Bicyclicmethyl Acetamide Compounds | PFIZER, INC. | 2006-11-30 | — | — | US | disclosed |