Piminodine

Piminodine

SCHEMBL26477

CCOC(=O)C1(c2ccccc2)CCN(CCCNc2ccccc2)CC1

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ KCNA3 P22001 2/20 0.71
▸ OPRM1 P35372 9/20 0.70
▸ OPRD1 P41143 8/20 0.70
▸ OPRK1 P41145 6/20 0.70
▸ SLC22A1 O15245 1/20 0.65
▸ SLC6A4 P31645 1/20 0.65
▸ ADRA1A P35348 1/20 0.65
▸ KCNH2 Q12809 1/20 0.65
▸ MEN1 O00255 1/20 0.61
▸ LMNA P02545 1/20 0.61
▸ KMT2A Q03164 1/20 0.61
▸ TDP1 Q9NUW8 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piminodine SCHEMBL1286844 0.96 KCNA3 (0.66) KCNA3OPRM1OPRD1OPRK1SLC22A1
Piminodine SCHEMBL676858 0.95 KCNA3 (0.64) KCNA3OPRM1OPRD1OPRK1SLC22A1
SCHEMBL11708747 0.86 KCNA3 (0.80) KCNA3OPRM1OPRD1OPRK1SLC22A1
SCHEMBL6197539 0.84 KCNA3 (0.77) KCNA3OPRM1OPRD1OPRK1SLC22A1
SCHEMBL11712840 0.83 OPRM1 (0.82) KCNA3OPRM1OPRD1OPRK1SLC22A1
Hydrochloric Acid SCHEMBL9064512 0.83 OPRM1 (0.75) KCNA3OPRM1OPRD1OPRK1SLC22A1
SCHEMBL7313939 0.83 KCNA3 (1.00) KCNA3OPRM1OPRD1OPRK1SLC22A1
SCHEMBL11601769 0.82 OPRM1 (0.80) KCNA3OPRM1OPRD1OPRK1SLC22A1
SCHEMBL9064841 0.82 KCNA3 (0.73) KCNA3OPRM1OPRD1OPRK1SLC22A1
SCHEMBL11712071 0.82 OPRM1 (1.00) KCNA3OPRM1OPRD1OPRK1SLC22A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6936 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724049-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF Catalent Ontario Limited (CA) 2026-04-15 — — EP claimed
US-20250319074-A1 TREATMENT AND MANAGEMENT OF AUGMENTATION IN RESTLESS LEGS SYNDROME UNIV EAST CAROLINA (US) 2025-10-16 — — US claimed
US-12383743-B2 Treatment of addiction and dependency TACA JR ARTURO C (US) 2025-08-12 — — US claimed
US-20250228771-A1 ALKALINE INTRAORAL PRODUCTS EMPLICURE AB (publ) (SE) 2025-07-17 — — US claimed
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 — — EP claimed
EP-4565202-A1 ALKALINE INTRAORAL PRODUCTS EMPLICURE AB (publ) (SE) 2025-06-11 — — EP claimed
WO-2024254056-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF CATALENT ONTARIO LIMITED (CA) 2024-12-12 — — WO claimed
US-12133922-B2 Abuse resistant capsule R.P. SCHERER TECHNOLOGIES, LLC (US) 2024-11-05 — — US claimed
US-12036192-B2 Combination treatments for opioid crisis PRESTI MICHAEL (US) 2024-07-16 — — US claimed
US-11964056-B1 Tamper resistant dosage forms PURDUE PHARMA L.P (US) 2024-04-23 — — US claimed
EP-0731694-A1 OPIOID FORMULATIONS FOR TREATING PAIN Euroceltique S.A. (LU) 1996-09-18 — — EP claimed
US-5556838-A BLOCKING N-METHYLASPARTATE RECEPTORS TO PREVENT ADDICTION VIRGINIA COMMONWEALTH UNIVERSITY (US) 1996-09-17 — — US claimed
CN-1130352-A Method for relieving pain by orally administering 24-hour sustained-release opioid dosage form capable of rapidly increasing initial blood concentration of patient EURO CELTIQUE SA (LU) 1996-09-04 — — CN claimed
WO-1996014058-A1 MELT-EXTRUDED ORALLY ADMINISTRABLE OPIOID FORMULATIONS EURO-CELTIQUE, S.A. (LU) 1996-05-17 — — WO claimed
WO-1995014460-A1 OPIOID FORMULATIONS FOR TREATING PAIN EURO-CELTIQUE S.A. (LU) 1995-06-01 — — WO claimed
EP-0647448-A1 Orally administrable opioid formulations having extended duration of effect Euroceltique S.A. (LU) 1995-04-12 — — EP claimed
EP-0608893-A1 Inhibiting the development of tolerance to and/or dependence on an additive substance VIRGINIA COMMONWEALTH UNIVERSITY (US) 1994-08-03 — — EP claimed
US-5321012-A Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance VIRGINIA COMMONWEALTH UNIVERSITY MEDICAL COLLEGE (US) 1994-06-14 — — US claimed
EP-0174342-B1 BRAIN-SPECIFIC ANALOGUES OF CENTRALLY ACTING AMINES UNIVERSITY OF FLORIDA (US) 1989-12-20 — — EP claimed
US-4126684-A 4-AMINO-3-P-HALOPHENYLBUTYRIC ACIDS AND THEIR DERIVATIVES USED IN THE CONTROL OF NARCOTIC ABUSE CIBA-GEIGY CORPORATION (US) 1978-11-21 — — US claimed
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