Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL28113027 | 0.81 | TSHR (0.39) | MAPTHSD11B1TP53ALDH1A1LMNA | |
| SCHEMBL26031172 | 0.80 | ALDH1A1 (0.47) | SMN1; SMN2KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL25067239 | 0.79 | TP53 (0.42) | SMN1; SMN2MAPTTP53ALDH1A1 | |
| SCHEMBL10516690 | 0.79 | SMN1; SMN2 (0.60) | SMN1; SMN2MAPTHSD11B1MEN1KMT2A | |
| SCHEMBL2657918 | 0.78 | — | — | |
| SCHEMBL1296764 | 0.78 | TSHR (0.43) | SMN1; SMN2HSD11B1KMT2ATP53ALDH1A1 | |
| SCHEMBL6990807 | 0.78 | MAPT (0.62) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL23396158 | 0.78 | HRH3 (0.50) | SMN1; SMN2MAPTHSD11B1TP53ALDH1A1 | |
| SCHEMBL7379802 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTHSD11B1ALDH1A1GAA | |
| SCHEMBL26030610 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTHSD11B1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072246-A1 | PROLYL HYDROXYLASE DOMAIN-CONTAINING PROTEIN (PHD) INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-04 | — | — | WO | disclosed |