Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10516690 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2HSD11B1MAPTALDH1A1GAA | |
| SCHEMBL20300145 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2HSD11B1MAPTALDH1A1GAA | |
| SCHEMBL5094316 | 0.79 | — | — | |
| SCHEMBL6990807 | 0.79 | MAPT (0.62) | SMN1; SMN2MAPTALDH1A1GAACYP3A4 | |
| SCHEMBL12156678 | 0.78 | SMN1; SMN2 (0.67) | SMN1; SMN2HSD11B1 | |
| SCHEMBL26030610 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2HSD11B1MAPTALDH1A1GAA | |
| SCHEMBL28492260 | 0.77 | ALDH1A1 (0.47) | SMN1; SMN2MAPTALDH1A1TSHR | |
| SCHEMBL7749087 | 0.76 | SMN1; SMN2 (0.55) | SMN1; SMN2HSD11B1MAPTALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL28671520 | 0.76 | SMN1; SMN2 (0.55) | SMN1; SMN2HSD11B1MAPTALDH1A1KDM4E | |
| SCHEMBL26477236 | 0.76 | SMN1; SMN2 (0.55) | SMN1; SMN2HSD11B1MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069143-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-30 | — | — | US | disclosed |
| EP-0885213-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0885213-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997025323-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-17 | — | — | WO | disclosed |