Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.40 |
| ▸ | CDK2 | P24941 | 4/20 | 0.40 |
| ▸ | CDK9 | P50750 | 4/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2647410 | 0.93 | L3MBTL1 (0.44) | L3MBTL1FFAR4CCNT1CDK2CDK9 | |
| SCHEMBL2648045 | 0.87 | L3MBTL1 (0.40) | L3MBTL1FFAR4CCNT1CDK2CDK9 | |
| SCHEMBL2647496 | 0.85 | FFAR4 (0.39) | L3MBTL1FFAR4CCNT1CDK2CDK9 | |
| SCHEMBL2647497 | 0.85 | FFAR4 (0.39) | L3MBTL1FFAR4CCNT1CDK2CDK9 | |
| SCHEMBL2648665 | 0.84 | FFAR4 (0.47) | L3MBTL1FFAR4CCNT1CDK2CDK9 | |
| SCHEMBL2649450 | 0.83 | L3MBTL1 (0.47) | L3MBTL1FFAR4CCNT1CDK2CDK9 | |
| SCHEMBL2647456 | 0.82 | CCNT1 (0.44) | L3MBTL1FFAR4CCNT1CDK2CDK9 | |
| SCHEMBL2646478 | 0.81 | L3MBTL1 (0.47) | L3MBTL1FFAR4CCNT1CDK2CDK9 | |
| SCHEMBL2648392 | 0.76 | L3MBTL1 (0.40) | L3MBTL1FFAR4CCNT1CDK2CDK9 | |
| SCHEMBL2648389 | 0.76 | L3MBTL1 (0.40) | L3MBTL1FFAR4CCNT1CDK2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218431-B1 | GLUCAGON RECEPTOR ANTAGONISTS FOR THERAPY OF DIABETES AND CONDITIONS ASSOCIATED WITH DIABETES | BAYER CORPORATION | 2001-04-17 | — | — | US | disclosed |
| EP-0934274-A1 | SUBSTITUTED PYRIDINES AND BIPHENYLS AS ANTI-HYPERCHOLESTERINEMIC, ANTI-HYPERLIPOPROTEINEMIC AND ANTI-HYPERGLYCEMIC AGENTS | Bayer Corporation (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998004528-A2 | SUBSTITUTED PYRIDINES AND BIPHENYLS AS ANTI-HYPERCHOLESTERINEMIC, ANTI-HYPERLIPOPROTEINEMIC AND ANTI-HYPERGLYCEMIC AGENTS | BAYER CORPORATION (US) | 1998-02-05 | — | — | WO | disclosed |