Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.47 |
| ▸ | CDK2 | P24941 | 5/20 | 0.46 |
| ▸ | CDK9 | P50750 | 5/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | GLRA1 | P23415 | 2/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2647410 | 0.91 | L3MBTL1 (0.44) | FFAR4CDK2CDK9CCNT1CCNA2 | |
| SCHEMBL2649450 | 0.90 | L3MBTL1 (0.47) | FFAR4CDK2CDK9CCNT1CCNA2 | |
| SCHEMBL2647456 | 0.89 | CCNT1 (0.44) | FFAR4CDK2CDK9CCNT1CCNA2 | |
| SCHEMBL2647845 | 0.84 | L3MBTL1 (0.43) | FFAR4CDK2CDK9CCNT1CCNA2 | |
| SCHEMBL2648045 | 0.83 | L3MBTL1 (0.40) | FFAR4CDK2CDK9CCNT1CCNA2 | |
| SCHEMBL2647497 | 0.81 | FFAR4 (0.39) | FFAR4CDK2CDK9CCNT1CCNA2 | |
| SCHEMBL2647496 | 0.81 | FFAR4 (0.39) | FFAR4CDK2CDK9CCNT1CCNA2 | |
| SCHEMBL2646478 | 0.76 | L3MBTL1 (0.47) | FFAR4CDK2CDK9CCNT1CCNA2 | |
| SCHEMBL1958139 | 0.75 | FFAR4 (0.75) | FFAR4L3MBTL1FFAR1LMNAHPGD | |
| SCHEMBL2648631 | 0.73 | GCGR (0.57) | FFAR4CDK2CDK9CCNT1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218431-B1 | GLUCAGON RECEPTOR ANTAGONISTS FOR THERAPY OF DIABETES AND CONDITIONS ASSOCIATED WITH DIABETES | BAYER CORPORATION | 2001-04-17 | — | — | US | disclosed |