SCHEMBL994667

SCHEMBL994667

NN1CCC(C(=O)O)CC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.44
PLG P00747 1/20 0.44
PLAT P00750 1/20 0.44
TSHR P16473 2/20 0.44
GABRP O00591 1/20 0.44
GABRD O14764 1/20 0.44
GABRA1 P14867 1/20 0.44
GABRB1 P18505 1/20 0.44
GABRG2 P18507 1/20 0.44
GABRB3 P28472 1/20 0.44
GABRA5 P31644 1/20 0.44
GABRA3 P34903 1/20 0.44
GABRA2 P47869 1/20 0.44
GABRB2 P47870 1/20 0.44
GABRA4 P48169 1/20 0.44
GABRE P78334 1/20 0.44
PMP22 Q01453 1/20 0.44
GABRA6 Q16445 1/20 0.44
GABRG1 Q8N1C3 1/20 0.44
GABRG3 Q99928 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5301962 0.85
SCHEMBL13533754 0.85
SCHEMBL13533879 0.85
SCHEMBL5074242 0.79 SMN1; SMN2 (0.56) KDM4EL3MBTL1HSD17B10SMN1; SMN2
SCHEMBL2647862 0.77 SMN1; SMN2 (0.39) LMNATSHRHPGDSMN1; SMN2
SCHEMBL5197245 0.76 TSHR (0.46) LMNAPLGPLATTSHRGABRP
SCHEMBL487980 0.75 LMNA (0.50) LMNAPLGPLATTSHRGABRP
SCHEMBL2239761 0.74 TSHR (0.44) LMNAPLGPLATTSHRGABRP
SCHEMBL21164663 0.74 TSHR (0.44) LMNAPLGPLATTSHRGABRP
SCHEMBL20502579 0.74 TSHR (0.44) LMNAPLGPLATTSHRGABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118772230-A Long-acting K opioid receptor agonist 成都奥达生物科技有限公司 2024-10-15 CN claimed
CN-116239651-A Liquid phase synthesis method of diclofenac 深圳翰宇药业股份有限公司 2023-06-09 CN claimed
CN-101535336-A Synthetic phthalamides and dimers thereof SYNTHETIC PEPTIDE AMIDES AND D (US) 2009-09-16 CN claimed
EP-1884513-A1 PYRAZOLE COMPOUND AND THERAPEUTIC AGENT FOR DIABETES COMPRISING THE SAME Japan Tobacco, Inc. (JP) 2008-02-06 EP claimed
US-20070032529-A1 Pyrazole compounds and their use as antidiabetes agents JAPAN TOBACCO INC. (JP) 2007-02-08 US claimed
WO-2005122379-A9 ALPHA-4 BETA-1 INTEGRIN LIGANDS FOR IMAGING AND THERAPY UNIV CALIFORNIA (US) 2006-03-09 WO claimed
CN-118772230-A Long-acting K opioid receptor agonist 成都奥达生物科技有限公司 2024-10-15 CN disclosed
EP-3521301-B1 POLYAMIDE COMPOUND AND USE THEREOF SICHUAN KELUN BIOTECH BIOPHARMACEUTICAL CO LTD (CN) 2024-03-06 EP disclosed
US-20230364096-A1 USE OF A COMBINATION COMPRISING A BTK INHIBITOR FOR TREATING CANCERS BEONE MEDICINES I GMBH (CH) 2023-11-16 US disclosed
CN-116239651-A Liquid phase synthesis method of diclofenac 深圳翰宇药业股份有限公司 2023-06-09 CN disclosed
US-20230152316-A1 SARS-COV2 SPIKE PROTEIN BINDING PEPTIDES MASSACHUSETTS INST TECHNOLOGY (US) 2023-05-18 US disclosed
EP-4146268-A2 METHODS OF DETECTING AND TREATING LUNG DAMAGE IN RESPIRATORY-RELATED VIRAL INFECTIONS The Regents of the University of California (US) 2023-03-15 EP disclosed
EP-3630771-B1 5,6-FUSED-BICYCLIC COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES NOVARTIS AG (CH) 2022-06-29 EP disclosed
US-20070032529-A1 Pyrazole compounds and their use as antidiabetes agents JAPAN TOBACCO INC. (JP) 2007-02-08 US disclosed
WO-2005122379-A9 ALPHA-4 BETA-1 INTEGRIN LIGANDS FOR IMAGING AND THERAPY UNIV CALIFORNIA (US) 2006-03-09 WO disclosed
WO-2005122379-A2 ALPHA-4 BETA-1 INTEGRIN LIGANDS FOR IMAGING AND THERAPY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-12-22 WO disclosed
EP-0172526-A1 Benzodiazepines, process for their preparation and their use Troponwerke GmbH & Co. KG (DE) 1986-02-26 EP disclosed
EP-0042570-B1 20-DEOXYROSARAMICIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SCHERING CORPORATION (US) 1983-10-19 EP disclosed
EP-0042570-A1 20-Deoxyrosaramicin derivatives, process for their preparation and pharmaceutical compositions containing them SCHERING CORPORATION (US) 1981-12-30 EP disclosed
US-4279896-A Novel 20-imino macrolide antibacterial agents SCHERING CORPORATION (US) 1981-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070032529-A1 Pyrazole compounds and their use as antidiabetes agents PYGL, GYS2, AGL LMNA 2123/4885PLG 1951/4885PLAT 2284/4885
US-20230364096-A1 USE OF A COMBINATION COMPRISING A BTK INHIBITOR FOR TREATING CANCERS BTK, LCK, LYN LMNA 4464/4885PLG 4628/4885PLAT 2868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.