Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2650489 | 0.88 | GCGR (0.44) | ALDH1A1MAPTLMNASMN1; SMN2APAF1 | |
| SCHEMBL2650486 | 0.88 | GCGR (0.44) | ALDH1A1MAPTLMNASMN1; SMN2APAF1 | |
| SCHEMBL2648908 | 0.88 | MAPT (0.39) | ALDH1A1MAPTLMNASMN1; SMN2APAF1 | |
| SCHEMBL2648110 | 0.88 | LDHA (0.40) | LDHAALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL2648905 | 0.88 | MAPT (0.39) | ALDH1A1MAPTLMNASMN1; SMN2APAF1 | |
| SCHEMBL2649163 | 0.85 | MAPT (0.36) | ALDH1A1MAPTLMNASMN1; SMN2APAF1 | |
| SCHEMBL2649161 | 0.85 | MAPT (0.36) | ALDH1A1MAPTLMNASMN1; SMN2APAF1 | |
| SCHEMBL2648083 | 0.83 | MAPT (0.41) | ALDH1A1MAPTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL2649051 | 0.82 | MAPT (0.45) | ALDH1A1MAPTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL2648214 | 0.82 | MAPT (0.48) | ALDH1A1MAPTLMNASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218431-B1 | GLUCAGON RECEPTOR ANTAGONISTS FOR THERAPY OF DIABETES AND CONDITIONS ASSOCIATED WITH DIABETES | BAYER CORPORATION | 2001-04-17 | — | — | US | disclosed |