Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.38 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27416860 | 0.99 | LMNA (0.48) | LMNAKMT2ATSHRALDH1A1CYP2D6 | |
| SCHEMBL27416853 | 0.97 | LMNA (0.49) | LMNAKMT2ATSHRALDH1A1CYP2D6 | |
| SCHEMBL27416867 | 0.93 | LMNA (0.51) | LMNAKMT2ATSHRALDH1A1CYP2D6 | |
| SCHEMBL22697508 | 0.90 | CYP2D6 (0.53) | LMNAKMT2ATSHRALDH1A1CYP2D6 | |
| SCHEMBL26350712 | 0.90 | CYP2D6 (0.53) | LMNAKMT2ATSHRALDH1A1CYP2D6 | |
| SCHEMBL9604424 | 0.90 | ALDH1A1 (0.42) | LMNAKMT2ATSHRALDH1A1CYP2D6 | |
| SCHEMBL16248647 | 0.90 | ALDH1A1 (0.42) | LMNAKMT2ATSHRALDH1A1CYP2D6 | |
| SCHEMBL27416844 | 0.90 | LMNA (0.48) | LMNAKMT2ATSHRALDH1A1CYP2D6 | |
| SCHEMBL18073843 | 0.89 | LMNA (0.57) | LMNAKMT2ATSHRALDH1A1CYP2D6 | |
| SCHEMBL17589419 | 0.89 | ALDH1A1 (0.41) | LMNAKMT2ATSHRALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240218023-A1 | CYCLIC PEPTIDE-N-ACETYLGALACTOSAMINE (GALNAC) CONJUGATES FOR DRUG DELIVERY TO LIVER CELLS | MICROBIO (SHANGHAI) CO., LTD. (CN) | 2024-07-04 | — | — | US | disclosed |
| US-20230139322-A1 | SiRNA molecule inhibiting the expression of the PCSK9 gene and use thereof | ARGORNA PHARMACEUTICALS LIMITED (CN) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230139322-A1 | SiRNA molecule inhibiting the expression of the PCSK9 gene and use thereof | PCSK9, PCSK7, PCSK6 | LMNA 400/4885KMT2A 1244/4885TSHR 4233/4885 |
| US-20240218023-A1 | CYCLIC PEPTIDE-N-ACETYLGALACTOSAMINE (GALNAC) CONJUGATES FOR DRUG DELIVERY TO LIVER CELLS | GALNT1, CSGALNACT1, GALNT2 | LMNA 1541/4885KMT2A 3597/4885TSHR 1210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.