SCHEMBL26482177

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL26482173	1.00	HDAC4 (0.48)	HDAC4HDAC2HDAC8HSD17B1HSD17B2
	SCHEMBL24960733	0.93	MCL1 (0.44)	HDAC4HDAC2HDAC8MCL1ACMSD
	SCHEMBL26482166	0.90	MCL1 (0.43)	HDAC8HSD17B1HSD17B2ESR2ESR1
	SCHEMBL26482175	0.89	MCL1 (0.43)	HSD17B1HSD17B2ESR2ESR1MCL1
	SCHEMBL26856185	0.88	PIM1 (0.41)	HDAC4HDAC2HDAC8HSD17B1HSD17B2
	SCHEMBL26891939	0.88	PIM1 (0.41)	HDAC4HDAC2HDAC8HSD17B1HSD17B2
	SCHEMBL24211489	0.88	PIM1 (0.44)	HDAC4HDAC2HDAC8HSD17B1HSD17B2
	SCHEMBL536536	0.88	PIM1 (0.47)	HDAC4HDAC2HDAC8HSD17B1HSD17B2
	SCHEMBL29350427	0.88	PIM1 (0.47)	HDAC4HDAC2HDAC8HSD17B1HSD17B2
	SCHEMBL15367037	0.87	PIM1 (0.43)	HDAC4HDAC2HDAC8HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.