Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.42 |
| ▸ | TUBB | P07437 | 4/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2335896 | 0.84 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2TSHRABCG2TUBB4A | |
| SCHEMBL30426642 | 0.84 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2TSHRABCG2TUBB4A | |
| SCHEMBL17518840 | 0.75 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2TSHRABCG2TDP1 | |
| SCHEMBL19835134 | 0.74 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2POLBTSHRTDP1 | |
| SCHEMBL2593503 | 0.74 | MCL1 (0.50) | ALDH1A1TSHRABCG2TUBB4ATUBB | |
| SCHEMBL4290 | 0.73 | — | — | |
| SCHEMBL17231887 | 0.73 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2POLBTDP1MAPK1 | |
| SCHEMBL29391648 | 0.73 | — | — | |
| SCHEMBL27220302 | 0.72 | HTR1A (0.50) | ALDH1A1SMN1; SMN2POLBABCG2MAPK1 | |
| SCHEMBL96635 | 0.72 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2TSHRTUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |