Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ODC1 | P11926 | 1/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.48 |
| ▸ | FDPS | P14324 | 2/20 | 0.48 |
| ▸ | ARG1 | P05089 | 3/20 | 0.47 |
| ▸ | ARG2 | P78540 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27406408 | 0.96 | ODC1 (0.58) | ODC1DNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL28564886 | 0.92 | ARG2 (0.53) | MEN1KMT2AALDH1A1SMPD1FDPS | |
| SCHEMBL21219814 | 0.92 | ARG2 (0.53) | MEN1KMT2AALDH1A1SMPD1FDPS | |
| SCHEMBL8590129 | 0.92 | ARG2 (0.53) | MEN1KMT2AALDH1A1SMPD1FDPS | |
| SCHEMBL3024369 | 0.92 | ARG2 (0.53) | MEN1KMT2AALDH1A1SMPD1FDPS | |
| SCHEMBL8719171 | 0.92 | ARG2 (0.53) | MEN1KMT2AALDH1A1SMPD1FDPS | |
| SCHEMBL31586115 | 0.92 | ARG2 (0.53) | MEN1KMT2AALDH1A1SMPD1FDPS | |
| SCHEMBL11421459 | 0.92 | ARG2 (0.53) | MEN1KMT2AALDH1A1SMPD1FDPS | |
| SCHEMBL28567340 | 0.92 | ARG2 (0.53) | MEN1KMT2AALDH1A1SMPD1FDPS | |
| SCHEMBL27855927 | 0.92 | ARG2 (0.53) | MEN1KMT2AALDH1A1SMPD1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2263087-B1 | LABELED REACTANTS AND THEIR USES | PACIFIC BIOSCIENCES CALIFORNIA INC (US) | 2017-08-09 | — | — | EP | disclosed |
| US-9587275-B2 | Single molecule sequencing with two distinct chemistry steps | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2017-03-07 | — | — | US | disclosed |
| US-9464107-B2 | Labeled nucleotide analogs | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-10-11 | — | — | US | disclosed |
| US-9447464-B2 | Single molecule sequencing with two distinct chemistry steps | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-09-20 | — | — | US | disclosed |
| US-20160010150-A1 | SINGLE MOLECULE SEQUENCING WITH TWO DISTINCT CHEMISTRY STEPS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2016-01-14 | — | — | US | disclosed |
| US-8906614-B2 | Labeled reactants and their uses | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| US-20140186825-A1 | LABELED NUCLEOTIDE ANALOGS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-07-03 | — | — | US | disclosed |
| US-20140127680-A1 | SINGLE MOLECULE SEQUENCING WITH TWO DISTINCT CHEMISTRY STEPS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-05-08 | — | — | US | disclosed |
| US-8603741-B2 | Single molecule sequencing with two distinct chemistry steps | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2013-12-10 | — | — | US | disclosed |
| US-20130183663-A1 | LABELED REACTANTS AND THEIR USES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2013-07-18 | — | — | US | disclosed |
| US-8133702-B2 | Engineered fluorescent dye labeled nucleotide analogs for DNA sequencing | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-13 | — | — | US | disclosed |
| US-20120028248-A1 | ENGINEERED FLUORESCENT DYE LABELED NUCLEOTIDE ANALOGS FOR DNA SEQUENCING | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-02-02 | — | — | US | disclosed |
| US-20110311964-A1 | LABELED REACTANTS AND THEIR USES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2011-12-22 | — | — | US | disclosed |
| US-20110212437-A1 | SINGLE MOLECULE SEQUENCING WITH TWO DISTINCT CHEMISTRY STEPS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2011-09-01 | — | — | US | disclosed |
| US-7973146-B2 | Engineered fluorescent dye labeled nucleotide analogs for DNA sequencing | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2011-07-05 | — | — | US | disclosed |
| US-7968702-B2 | Labeled reactants and their uses | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2011-06-28 | — | — | US | disclosed |
| EP-2263087-A1 | LABELED REACTANTS AND THEIR USES | Pacific Biosciences of California, Inc. (US) | 2010-12-22 | — | — | EP | disclosed |
| US-20090246791-A1 | ENGINEERED FLUORESCENT DYE LABELED NUCLEOTIDE ANALOGS FOR DNA SEQUENCING | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2009-10-01 | — | — | US | disclosed |
| US-20090233302-A1 | LABELED REACTANTS AND THEIR USES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2009-09-17 | — | — | US | disclosed |
| WO-2009114182-A1 | LABELED REACTANTS AND THEIR USES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2009-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212437-A1 | SINGLE MOLECULE SEQUENCING WITH TWO DISTINCT CHEMISTRY STEPS | RNGTT, POLL, NUDT21 | ODC1 1540/4885DNM1 584/4885MEN1 2872/4885 |
| US-20090246791-A1 | ENGINEERED FLUORESCENT DYE LABELED NUCLEOTIDE ANALOGS FOR DNA SEQUENCING | POLM, POLN, POLB | ODC1 1597/4885DNM1 666/4885MEN1 4570/4885 |
| US-20120028248-A1 | ENGINEERED FLUORESCENT DYE LABELED NUCLEOTIDE ANALOGS FOR DNA SEQUENCING | POLN, POLM, RNGTT | ODC1 828/4885DNM1 669/4885MEN1 4514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.