Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.66 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTR7 | P34969 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL138121 | 0.80 | NPSR1 (1.00) | ALDH1A1TSHRHPGDLMNANFKB1 | |
| SCHEMBL29350604 | 0.80 | NPSR1 (1.00) | ALDH1A1TSHRHPGDLMNANFKB1 | |
| SCHEMBL6240736 | 0.78 | TSHR (0.69) | ALDH1A1TSHRHPGDLMNANFKB1 | |
| SCHEMBL5067817 | 0.78 | TSHR (0.69) | ALDH1A1TSHRHPGDLMNANFKB1 | |
| SCHEMBL31238472 | 0.78 | TSHR (0.69) | ALDH1A1TSHRHPGDLMNANFKB1 | |
| SCHEMBL1664328 | 0.78 | HPGD (0.73) | ALDH1A1TSHRHPGDLMNANFKB1 | |
| SCHEMBL6116786 | 0.78 | TSHR (0.69) | ALDH1A1TSHRHPGDLMNANFKB1 | |
| SCHEMBL1615011 | 0.78 | TSHR (0.69) | ALDH1A1TSHRHPGDLMNANFKB1 | |
| SCHEMBL1519655 | 0.78 | TSHR (0.69) | ALDH1A1TSHRHPGDLMNANFKB1 | |
| SCHEMBL2260803 | 0.78 | TSHR (1.00) | ALDH1A1TSHRHPGDLMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |