Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 14/20 | 0.50 |
| ▸ | CKS1B | P61024 | 1/20 | 0.47 |
| ▸ | SKP1 | P63208 | 1/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.47 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20149913 | 0.91 | SUV39H2 (0.48) | SUV39H2CKS1BSKP1SKP2KDM4D | |
| SCHEMBL38659211 | 0.86 | KDM4E (0.49) | SUV39H2CKS1BSKP1SKP2KDM4D | |
| SCHEMBL15759214 | 0.85 | CKS1B (0.47) | CKS1BSKP1SKP2KDM4D | |
| SCHEMBL4442557 | 0.85 | CKS1B (0.47) | CKS1BSKP1SKP2NPC1RAB9A | |
| SCHEMBL20133857 | 0.84 | DRD2 (0.60) | SUV39H2CKS1BSKP1SKP2 | |
| SCHEMBL4443945 | 0.82 | CKS1B (0.47) | CKS1BSKP1SKP2 | |
| SCHEMBL12283995 | 0.81 | SUV39H2 (0.49) | SUV39H2KDM4D | |
| SCHEMBL4433773 | 0.81 | MAPT (0.50) | CKS1BSKP1SKP2 | |
| SCHEMBL12069190 | 0.80 | CKS1B (0.45) | SUV39H2CKS1BSKP1SKP2 | |
| SCHEMBL517675 | 0.80 | SUV39H2 (0.45) | SUV39H2CKS1BSKP1SKP2KDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075479-A1 | NOVEL THIENO[2,3-D]PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER OR AUTOIMMUNE DISEASE COMPRISING SAME AS ACTIVE INGREDIENT | 재단법인 대구경북첨단의료산업진흥재단 | 2023-05-04 | — | — | WO | disclosed |