Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.60 |
| ▸ | CKS1B | P61024 | 1/20 | 0.54 |
| ▸ | SKP1 | P63208 | 1/20 | 0.54 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.54 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.53 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.53 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.53 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.53 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.53 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.53 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.53 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.53 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.53 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.53 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.53 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.53 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17384450 | 0.94 | PIM1 (0.59) | DRD2CKS1BSKP1SKP2CACNB4 | |
| SCHEMBL34463006 | 0.89 | DRD2 (0.58) | DRD2CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL20129729 | 0.87 | CKS1B (0.52) | DRD2CKS1BSKP1SKP2PIM1 | |
| SCHEMBL20129730 | 0.86 | CKS1B (0.51) | DRD2CKS1BSKP1SKP2PIM1 | |
| SCHEMBL7716782 | 0.85 | DRD2 (0.69) | DRD2DRD3 | |
| SCHEMBL20149913 | 0.84 | SUV39H2 (0.48) | CKS1BSKP1SKP2CACNB4CACNA1A | |
| SCHEMBL26484666 | 0.84 | SUV39H2 (0.50) | CKS1BSKP1SKP2SUV39H2 | |
| SCHEMBL20140998 | 0.84 | MCOLN2 (0.55) | DRD2DRD3MCOLN2MCOLN1MEN1 | |
| SCHEMBL1271996 | 0.84 | CKS1B (0.55) | DRD2CKS1BSKP1SKP2PIM1 | |
| SCHEMBL19284706 | 0.82 | CKS1B (0.57) | DRD2CKS1BSKP1SKP2PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2020-11-24 | — | — | US | disclosed |
| US-20200207716-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. | 2020-07-02 | — | — | US | disclosed |
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| US-10414727-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2019-09-17 | — | — | US | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| US-20180127370-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | MTOR, RICTOR, RPTOR | DRD2 3229/4885CKS1B 2986/4885SKP1 1767/4885 |
| US-10414727-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | MTOR, RICTOR, RPTOR | DRD2 3229/4885CKS1B 2986/4885SKP1 1767/4885 |
| US-20180127370-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | MTOR, RICTOR, RPTOR | DRD2 3229/4885CKS1B 2986/4885SKP1 1767/4885 |
| US-20200207716-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | MTOR, RICTOR, RPTOR | DRD2 3229/4885CKS1B 2986/4885SKP1 1767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.