Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.38 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2648651 | 1.00 | SLC10A2 (0.43) | SLC10A2TP53MDM2GCGRLMNA | |
| SCHEMBL2647327 | 0.93 | SLC10A2 (0.43) | SLC10A2TP53MDM2GCGRLMNA | |
| SCHEMBL2647468 | 0.92 | SLC10A2 (0.44) | SLC10A2GCGRLMNAMAPTALDH1A1 | |
| SCHEMBL2647466 | 0.92 | SLC10A2 (0.44) | SLC10A2GCGRLMNAMAPTALDH1A1 | |
| SCHEMBL2649455 | 0.91 | SLC10A2 (0.43) | SLC10A2GCGRLMNAMAPTALDH1A1 | |
| SCHEMBL2650698 | 0.91 | SLC10A2 (0.43) | SLC10A2GCGRLMNAMAPTALDH1A1 | |
| SCHEMBL2648214 | 0.90 | MAPT (0.48) | SLC10A2TP53LMNAMAPTALDH1A1 | |
| SCHEMBL2649264 | 0.90 | GCGR (0.50) | SLC10A2GCGRMAPTALDH1A1THRB | |
| SCHEMBL2648215 | 0.90 | MAPT (0.48) | SLC10A2TP53LMNAMAPTALDH1A1 | |
| SCHEMBL2649262 | 0.90 | GCGR (0.50) | SLC10A2GCGRMAPTALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218431-B1 | GLUCAGON RECEPTOR ANTAGONISTS FOR THERAPY OF DIABETES AND CONDITIONS ASSOCIATED WITH DIABETES | BAYER CORPORATION | 2001-04-17 | — | — | US | disclosed |