Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15199110 | 0.83 | GAA (0.58) | GAASMN1; SMN2ALDH1A1KDM4ECYP2C9 | |
| SCHEMBL14241975 | 0.82 | GAA (0.65) | GAASMN1; SMN2ALDH1A1KDM4ECYP2C9 | |
| SCHEMBL23480154 | 0.82 | GAA (0.65) | GAASMN1; SMN2ALDH1A1KDM4ECYP2C9 | |
| SCHEMBL16437470 | 0.79 | CHRNB2 (0.58) | GAASMN1; SMN2KDM4ECHRNB2CHRNB4 | |
| SCHEMBL27125632 | 0.79 | CHRNB2 (0.58) | GAASMN1; SMN2KDM4ECHRNB2CHRNB4 | |
| SCHEMBL25463788 | 0.78 | CHRNB2 (0.56) | GAASMN1; SMN2KDM4ECHRNB2CHRNB4 | |
| SCHEMBL2991158 | 0.78 | CHRNB2 (0.71) | GAASMN1; SMN2ALDH1A1KDM4ECYP2C9 | |
| SCHEMBL24567736 | 0.77 | GAA (0.61) | GAASMN1; SMN2ALDH1A1KDM4ECYP2C9 | |
| SCHEMBL24567524 | 0.77 | GAA (0.51) | GAASMN1; SMN2ALDH1A1KDM4ECYP2C9 | |
| SCHEMBL10308293 | 0.77 | GAA (0.61) | GAASMN1; SMN2ALDH1A1KDM4ECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230323345-A1 | UNA OLIGOMERS FOR THE TREATMENT OF POLYGLUTAMINE DISEASES | ARCTURUS THERAPEUTICS, INC. | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230323345-A1 | UNA OLIGOMERS FOR THE TREATMENT OF POLYGLUTAMINE DISEASES | UPF1, HNRNPUL1, HNRNPUL2 | GAA 240/4885SMN1; SMN2 184/4885ALDH1A1 4397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.