Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 8/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 4/20 | 0.32 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21045696 | 0.78 | TRPC6 (0.57) | TRPC6CACNA1HGPR88 | |
| SCHEMBL21045688 | 0.77 | TRPC6 (0.56) | TRPC6CACNA1HSCN9A | |
| SCHEMBL30439833 | 0.77 | TRPC6 (0.56) | TRPC6CACNA1HSCN9A | |
| SCHEMBL23426470 | 0.76 | TRPC6 (0.44) | TRPC6SCN9A | |
| SCHEMBL23426476 | 0.74 | TRPC6 (0.45) | TRPC6 | |
| SCHEMBL23426479 | 0.72 | TRPC6 (0.39) | TRPC6MGAMGAASIMGAM2 | |
| SCHEMBL23047395 | 0.70 | PDGFRB (0.47) | TRPC6 | |
| SCHEMBL17811809 | 0.70 | PDE4B (0.40) | TRPC6ACACBGPR88MAOA | |
| SCHEMBL17815741 | 0.70 | ACHE (0.49) | TRPC6GAAMAOA | |
| SCHEMBL26488081 | 0.69 | PDGFRB (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49699-E1 | Inhibitors of TRPC6 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-10-17 | — | — | US | disclosed |