Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10898016 | 0.86 | HCRTR2 (0.48) | HCRTR2MAPT | |
| SCHEMBL9431997 | 0.83 | TRPV1 (0.41) | NPC1PTGDR2HCRTR2 | |
| SCHEMBL5846860 | 0.83 | SLC6A4 (0.39) | — | |
| SCHEMBL5846862 | 0.83 | SLC6A4 (0.39) | — | |
| SCHEMBL5846869 | 0.83 | SLC6A4 (0.39) | — | |
| SCHEMBL23705293 | 0.83 | ADRA2A (0.42) | ADRA2ANPC1PTGDR2HCRTR2MAPT | |
| SCHEMBL27395538 | 0.83 | MAP3K14 (0.46) | MAP3K14ADRA2ANPC1PTGDR2HCRTR2 | |
| SCHEMBL4879254 | 0.83 | NPC1 (0.45) | MAP3K14NPC1TP53MAPTTHRB | |
| SCHEMBL1846189 | 0.82 | MAP3K14 (0.50) | MAP3K14ADRA2APTGDR2 | |
| SCHEMBL5847548 | 0.82 | TSHR (0.37) | PTGDR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023195529-A1 | URACIL DERIVATIVE HAVING VIRAL GROWTH INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 塩野義製薬株式会社 | 2023-10-12 | — | — | WO | disclosed |
| WO-2023195530-A1 | URACIL DERIVATIVE HAVING VIRAL GROWTH INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 塩野義製薬株式会社 | 2023-10-12 | — | — | WO | disclosed |