Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 3/20 | 0.42 |
| ▸ | RARB | P10826 | 3/20 | 0.42 |
| ▸ | RARG | P13631 | 3/20 | 0.42 |
| ▸ | MAP3K14 | Q99558 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22975883 | 0.73 | KDM1A (0.43) | BACE1 | |
| SCHEMBL21344593 | 0.73 | KDM1A (0.43) | BACE1 | |
| SCHEMBL5736873 | 0.72 | HTT (0.40) | RARBRARGNPC1TP53MAPT | |
| SCHEMBL18211725 | 0.70 | MAP3K14 (0.50) | RARARARBRARGMAP3K14APP | |
| SCHEMBL6605548 | 0.69 | MAP3K14 (0.49) | RARARARBRARGMAP3K14NPC1 | |
| SCHEMBL5399703 | 0.69 | MAP3K14 (0.49) | RARARARBRARGMAP3K14NPC1 | |
| SCHEMBL6605552 | 0.69 | MAP3K14 (0.49) | RARARARBRARGMAP3K14NPC1 | |
| SCHEMBL6606788 | 0.69 | MAP3K14 (0.43) | RARARARBRARGMAP3K14NPC1 | |
| SCHEMBL6761742 | 0.69 | MAP3K14 (0.43) | RARARARBRARGMAP3K14NPC1 | |
| SCHEMBL26488609 | 0.68 | APLNR (0.43) | TP53MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023195529-A1 | URACIL DERIVATIVE HAVING VIRAL GROWTH INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 塩野義製薬株式会社 | 2023-10-12 | — | — | WO | disclosed |
| WO-2023195530-A1 | URACIL DERIVATIVE HAVING VIRAL GROWTH INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 塩野義製薬株式会社 | 2023-10-12 | — | — | WO | disclosed |