Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26488607 | 0.68 | RARA (0.42) | TP53MAPTTHRB | |
| SCHEMBL6578320 | 0.67 | SMN1; SMN2 (0.42) | ALDH1A1TP53MAPTPKMKMT2A | |
| SCHEMBL8793923 | 0.66 | AKR1B1 (0.46) | ALDH1A1HPGDTP53MAPTPKM | |
| SCHEMBL2295795 | 0.66 | APLNR (0.58) | APLNRALDH1A1HPGDTP53MAPT | |
| SCHEMBL5124837 | 0.66 | APLNR (0.55) | APLNRMC4RALDH1A1KMT2ATSHR | |
| SCHEMBL783785 | 0.65 | APLNR (1.00) | APLNRALDH1A1KMT2ATSHRMEN1 | |
| SCHEMBL14934456 | 0.65 | APLNR (0.56) | APLNRALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL19431069 | 0.65 | APLNR (0.56) | APLNRALDH1A1TP53MAPTKMT2A | |
| SCHEMBL8792757 | 0.64 | AKR1B1 (0.49) | ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL23705042 | 0.64 | RARA (0.37) | MAPTKMT2AHTTNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023195529-A1 | URACIL DERIVATIVE HAVING VIRAL GROWTH INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 塩野義製薬株式会社 | 2023-10-12 | — | — | WO | disclosed |
| WO-2023195530-A1 | URACIL DERIVATIVE HAVING VIRAL GROWTH INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 塩野義製薬株式会社 | 2023-10-12 | — | — | WO | disclosed |