Butyrylhydroxamic Acid

Butyrylhydroxamic Acid

SCHEMBL264922

CCCC(=O)NO

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyrylhydroxamic Acid SCHEMBL15650014 0.97
Butyrylhydroxamic Acid SCHEMBL28644579 0.92 HDAC2 (0.84)
SCHEMBL402760 0.82
Hydrochloric Acid SCHEMBL31229280 0.80
SCHEMBL742031 0.80
SCHEMBL15598241 0.80 HDAC3 (0.65)
Succinodihydroxamic Acid SCHEMBL940650 0.79 FOLH1 (0.75)
SCHEMBL23203038 0.78 HSP90AA1 (1.00)
SCHEMBL331039 0.78 HSP90AA1 (1.00)
SCHEMBL7945790 0.78 HSP90AA1 (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 400 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250297134-A1 HIGH RATE BULK OXIDE CMP COMPOSITION ENTEGRIS, INC. 2025-09-25 US claimed
EP-4049665-B1 METHODS AND COMPOSITIONS RELATING TO HEMATOPOIETIC STEM CELL EXPANSION CHILDRENS MEDICAL CT CORP (US) 2025-03-12 EP claimed
CN-118974253-A Therapeutic application of CRISPR V-type system 卡里布生物科学公司 2024-11-15 CN claimed
EP-3313420-B1 METHODS AND COMPOSITIONS RELATING TO HEMATOPOIETIC STEM CELL EXPANSION, ENRICHMENT, AND MAINTENANCE CHILDRENS MEDICAL CT CORP (US) 2024-03-13 EP claimed
US-11891625-B2 Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance CHILDREN'S MEDICAL CENTER CORPORATION 2024-02-06 US claimed
CN-110066281-B Multi-target anti-tumor activity evodiamine derivative, and preparation method and application thereof 中国人民解放军第二军医大学 2024-01-30 CN claimed
CN-117043157-A ERAP inhibitors 里尔大学 2023-11-10 CN claimed
WO-2023201270-A2 THERAPEUTIC APPLICATIONS OF CRISPR TYPE V SYSTEMS CARIBOU BIOSCIENCES, INC. (US) 2023-10-19 WO claimed
CN-115286583-A Diphenylaminopyrimidine-containing compound, preparation and application thereof as HDACs enzyme inhibitor 山东大学 2022-11-04 CN claimed
CN-115260690-A Visible light response supramolecular hydrogel and preparation method and application thereof 复旦大学 2022-11-01 CN claimed
WO-2003051825-A1 HUMAN ADAM-10 INHIBITORS EXELIXIS, INC. (US) 2003-06-26 WO claimed
US-6455589-B1 AN ORALLY ADMINISTRABLE EFFECTIVE UNIT SOLID DOSAGE OF A PRIMARY N-HYDROXYLAMINE OR A SALT, FREE OF NITRONE; USEFUL FOR REDUCING OXIDATIVE DAMAGE OR DELAYING SENESCENCE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2002-09-24 US claimed
US-6403647-B1 PROPRIONYL OR BUTYRYL HYDROXAMATE, OR SUBEROYL BIS HYDROXAMIC ACID TO STIMULATE EXPRESSION OF GLOBIN PROTEIN OR DEVELOPMENT OF ERYTHROID, MYELOID, OR MEGAKARYOTIC CELLS; TREATS ANEMIA; FREQUENCY OF DOSE LONGER THAN IN-VIVO HALF-LIFE OF COMPOUND Perrine, Susan P. 2002-06-11 US claimed
EP-1073633-A2 SUBSTITUTED BETA-AMINO ACID INHIBITORS OF METHIONINE AMINOPEPTIDASE-2 ABBOTT LABORATORIES (US) 2001-02-07 EP claimed
WO-1999057098-A2 SUBSTITUTED BETA-AMINO ACID INHIBITORS OF METHIONINE AMINOPEPTIDASE-2 ABBOTT LABORATORIES (US) 1999-11-11 WO claimed
EP-0577473-B1 Reducing cosmetic composition for the permanent deformation of hair based on a mercaptoalkylamino-amide and process for the permanent deformation of hair OREAL (FR) 1995-12-20 EP claimed
WO-1994005627-A1 HYDROXAMIC ACID-BASED BIFUNCTIONAL CHELATING COMPOUNDS UAB RESEARCH FOUNDATION (US) 1994-03-17 WO claimed
EP-0577473-A1 Reducing cosmetic composition for the permanent deformation of hair based on a mercaptoalkylamino-amide and process for the permanent deformation of hair L'OREAL (FR) 1994-01-05 EP claimed
EP-0491003-A1 OXIDATIVE HAIR DYE WITH LEVELLING ACTION. HENKEL KGAA (DE) 1992-06-24 EP claimed
WO-1991003230-A1 OXIDATIVE HAIR DYE WITH LEVELLING ACTION HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1991-03-21 WO claimed