Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9300666 | 0.82 | SERPINE1 (0.70) | PTGS1PTGS2SERPINE1CA1CA2 | |
| SCHEMBL416745 | 0.82 | FLT1 (0.53) | CA1CA2CA9MEN1CASP6 | |
| SCHEMBL1803937 | 0.80 | PTGS1 (0.66) | PTGS1PTGS2CA1CA2CA9 | |
| SCHEMBL20651836 | 0.79 | MEP1B (0.53) | CA1CA2CA9MEN1CASP6 | |
| SCHEMBL68932 | 0.78 | GAA (0.57) | HSD17B3HSD17B2PTGS1PTGS2SERPINE1 | |
| SCHEMBL9341624 | 0.78 | GAA (0.57) | HSD17B3HSD17B2PTGS1PTGS2SERPINE1 | |
| SCHEMBL29598983 | 0.78 | GAA (0.57) | HSD17B3HSD17B2PTGS1PTGS2SERPINE1 | |
| SCHEMBL6262301 | 0.78 | FLT1 (0.57) | PTGS1PTGS2CA2MEN1CASP6 | |
| SCHEMBL10993669 | 0.78 | FLT1 (0.56) | PTGS1PTGS2CA1CA2CA9 | |
| SCHEMBL10904392 | 0.77 | ALDH1A1 (0.49) | HSD17B3HSD17B2SERPINE1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |