Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2649460 | 0.88 | IDH1 (0.32) | IDH1ALDH1A1MAPTRAB9A | |
| SCHEMBL1342907 | 0.86 | MAPT (0.34) | IDH1ALDH1A1MAPTRAB9A | |
| SCHEMBL2650482 | 0.83 | IDH1 (0.35) | IDH1ALDH1A1MAPT | |
| SCHEMBL2651015 | 0.82 | CASR (0.33) | ALDH1A1MAPTCASRRAB9A | |
| SCHEMBL2651114 | 0.80 | — | — | |
| SCHEMBL1342169 | 0.79 | CCNE1 (0.31) | MAPT | |
| SCHEMBL1341478 | 0.78 | CNR1 (0.32) | MAPTRAB9A | |
| SCHEMBL1342612 | 0.76 | AXL (0.36) | IDH1ALDH1A1MAPTRAB9A | |
| SCHEMBL1340902 | 0.76 | MAPT (0.34) | IDH1ALDH1A1MAPTRAB9A | |
| SCHEMBL1342641 | 0.76 | GHSR (0.35) | IDH1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |