Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GHSR | Q92847 | 3/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.30 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1342907 | 0.95 | MAPT (0.34) | IDH1ALDH1A1MAPTGHSRCHRNA4 | |
| SCHEMBL1342169 | 0.91 | CCNE1 (0.31) | MAPTMEN1KMT2A | |
| SCHEMBL2649453 | 0.88 | IDH1 (0.31) | IDH1ALDH1A1MAPTRAB9A | |
| SCHEMBL1341478 | 0.86 | CNR1 (0.32) | MAPTRAB9AMEN1KMT2A | |
| SCHEMBL1342612 | 0.86 | AXL (0.36) | IDH1ALDH1A1MAPTGHSRCHRNA4 | |
| SCHEMBL1342641 | 0.85 | GHSR (0.35) | IDH1ALDH1A1MAPTGHSRCHRNA4 | |
| SCHEMBL1342690 | 0.85 | CASR (0.39) | ALDH1A1MAPTGHSRCHRNA4SLC6A3 | |
| SCHEMBL1340902 | 0.84 | MAPT (0.34) | IDH1ALDH1A1MAPTGHSRCHRNA4 | |
| SCHEMBL1342466 | 0.84 | ALDH1A1 (0.33) | ALDH1A1MAPTRAB9ANTRK1NTRK2 | |
| SCHEMBL1341180 | 0.84 | GHSR (0.35) | ALDH1A1MAPTGHSRCHRNA4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |