Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10939067 | 0.84 | MEN1 (0.53) | ACP3MEN1KMT2APARP1ALDH1A1 | |
| SCHEMBL6628518 | 0.82 | ACP3 (0.46) | ACP3MEN1KMT2APARP1ALDH1A1 | |
| SCHEMBL7283486 | 0.82 | PARP1 (0.50) | ACP3MEN1KMT2APARP1ALDH1A1 | |
| SCHEMBL11628563 | 0.82 | ACP3 (0.49) | ACP3MEN1KMT2APARP1ALDH1A1 | |
| SCHEMBL11750152 | 0.79 | PARP1 (0.52) | ACP3MEN1KMT2APARP1ALDH1A1 | |
| SCHEMBL8820615 | 0.79 | TPMT (0.41) | MEN1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL6556758 | 0.78 | ACP3 (0.46) | ACP3MEN1KMT2APARP1ALDH1A1 | |
| SCHEMBL9297070 | 0.78 | ACP3 (0.46) | ACP3MEN1KMT2APARP1ALDH1A1 | |
| SCHEMBL9297066 | 0.78 | ACP3 (0.46) | ACP3MEN1KMT2APARP1ALDH1A1 | |
| SCHEMBL11263818 | 0.78 | ACHE (0.46) | ACP3MEN1KMT2APARP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108707114-A | A kind of acetamides and its preparation method and application | 上海泰禾国际贸易有限公司 | 2018-10-26 | — | — | CN | disclosed |
| US-10071994-B2 | N-sulfonyl homoserine lactone derivatives, preparation method and use thereof | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA (CN) | 2018-09-11 | — | — | US | disclosed |
| US-20180179193-A1 | N-Sulfonyl Homoserine Lactone Derivatives, Preparation Method and Use Thereof | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA (CN) | 2018-06-28 | — | — | US | disclosed |
| EP-3150594-A1 | N-SULFONYL HOMOSERINE LACTONE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE | Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China (CN) | 2017-04-05 | — | — | EP | disclosed |
| EP-1212324-B1 | IMIDAZO-TRIAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME (GB) | 2003-10-29 | — | — | EP | disclosed |
| US-6608062-B1 | Ligands for gamma-aminobutyric acid receptors; treatment and/or prevention of central nervous system disorders, including anxiety | MERCK SHARP & DOHME LTD. | 2003-08-19 | — | — | US | disclosed |
| EP-1212324-A1 | IMIDAZO-TRIAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LTD. (GB) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001014377-A1 | IMIDAZO-TRIAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 2001-03-01 | — | — | WO | disclosed |
| US-4960457-A | Substituted 1,3-diphenyl pyrrolidones and their use as herbicides | ICI AMERICAS INC. (US) | 1990-10-02 | — | — | US | disclosed |
| US-4502883-A | CONTAINING CHLORINE | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1985-03-05 | — | — | US | disclosed |
| US-4455164-A | HALOGENATED DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1984-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180179193-A1 | N-Sulfonyl Homoserine Lactone Derivatives, Preparation Method and Use Thereof | LSS, SOS1, STS | ACP3 4669/4885MEN1 346/4885KMT2A 3793/4885 |
| US-10071994-B2 | N-sulfonyl homoserine lactone derivatives, preparation method and use thereof | LSS, SOS1, STS | ACP3 4643/4885MEN1 432/4885KMT2A 3890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.