Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.40 |
| ▸ | F13A1 | P00488 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | TGM1 | P22735 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KRAS | P01116 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30591753 | 0.92 | HSD11B1 (0.44) | GAABTKHSD11B1TRPV1F13A1 | |
| SCHEMBL26105982 | 0.92 | HSD11B1 (0.44) | GAABTKHSD11B1TRPV1F13A1 | |
| SCHEMBL26496957 | 0.86 | BTK (0.42) | GAABTKHSD11B1TRPV1F13A1 | |
| SCHEMBL30591767 | 0.80 | TRPV1 (0.44) | GAAHSD11B1TRPV1ALDH1A1NPSR1 | |
| SCHEMBL26497733 | 0.80 | TRPV1 (0.44) | GAAHSD11B1TRPV1NPSR1KRAS | |
| SCHEMBL26497743 | 0.79 | GAA (0.41) | GAAHSD11B1TRPV1F13A1TGM2 | |
| SCHEMBL30591869 | 0.78 | HTR1A (0.41) | GAABTKHSD11B1TRPV1F13A1 | |
| SCHEMBL26108174 | 0.78 | HTR1A (0.41) | GAABTKHSD11B1TRPV1F13A1 | |
| SCHEMBL30591947 | 0.76 | TRPV1 (0.50) | GAAHSD11B1TRPV1ALDH1A1NPSR1 | |
| SCHEMBL26111510 | 0.76 | TRPV1 (0.50) | GAAHSD11B1TRPV1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | disclosed |